Results 71 to 80 of about 3,349,054 (303)
The paper presents a general formal framework representing the role of balancing of values in interpretation of statutory rules. The model developed here is an extension of the model of teleological interpretation, where a given interpretive outcome is justified if it satisfies a given goal (or a set of goals).
Michal Araszkiewicz, Tomasz Zurek
openaire +3 more sources
Combining traditional nutrient load analysis with storm hydrograph separation reveals concealed patterns in event-driven nutrient export in a rural headwater catchment [PDF]
Flushing and dilution are major phenomena of solute export dynamics during precipitation events in headwater catchments but are hard to predict, even if catchment properties are well known.
L. Ditzel, C. Spill, M. Gassmann
doaj +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Work Life Balance – What Balance? [PDF]
“Never get so busy making a living that you forget to make a life.” Anonymous. This quote stands out because as we highlight our career goals and strategically plan for them, our personal lives often happen as an afterthought. To be successful at achieving a work–life balance, we should pay equal attention to planning all spheres of our life. While God
openaire +3 more sources
Prefrontal cortical activation measured by fNIRS during walking: effects of age, disease and secondary task [PDF]
Background Cognitive processes are required during walking to appropriately respond to environmental and task demands. There are now many studies that have used functional Near-Infrared Spectroscopy (fNIRS) to record brain activation to investigate ...
Paulo H.S. Pelicioni +3 more
doaj +2 more sources
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Background Two chronic forms of dizziness—bilateral vestibulopathy (BVP) with a loss of vestibular input, and functional dizziness with normal vestibular function—present with the key symptom of postural and gait imbalance.
Vivien Oertle +4 more
doaj +1 more source

