Results 111 to 120 of about 1,250,952 (308)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Associated factors of balance dysfunction and its correlation with functional lower limb muscle strength in middle-aged and older adults: an analysis based on CHARLS database

Zhongguo kangfu lilun yu shijian
Objective To identify the multidimensional factors influencing balance dysfunction in middle-aged and older adults, providing evidence-based support for the precise identification of high-risk individuals and the formulation of fall prevention strategies.
ZHANG Jihui, YI Longyue, YANG Yuanbin
doaj   +1 more source

Effects of motor imagery on walking function and balance in patients after stroke: A quantitative synthesis of randomized controlled trials

, 2017
Objective: This study aimed to evaluate the effects of motor imagery (MI) on walking function and balance in patients after stroke. Methods: Related randomized controlled trials (RCTs) were searched in 12 electronic databases (Cochrane Central Register ...
Wen-Ying Lin, Lin, Wen-Ying, Jing-Yu Tan, Zhuang-Miao Li, Gu-Lan Chen, Li, Rong-Qing, Rong-Qing Li, Li, Zhuang-Miao, Tan, Jing-Yu, Chen, Gu-Lan   +9 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Estimating The Cyclically Adjusted Budget Balance For The Romanian Economy. A Robust Approach [PDF]

This paper provides estimates for the structural fiscal balance for the Romanian economy over the period 1998-2008. The calculation of the structural fiscal balance is useful, since it provides a clear picture of the fiscal stance of the economy and it ...
Necula, Ciprian, Altar, Moisa, Bobeica, Gabriel   +2 more
core  

Modeling Acid–Base by Minimizing Charge-Balance

, 2019
In this study, we show that equilibrium pH can be obtained for any specified fluid with any number of buffers and dissociations. This is done by root finding in the equation for charge balance.
John A. Kellum (330062), Troels Ring (3121551)   +1 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Proprioceptive changes impair balance control in individuals with chronic obstructive pulmonary disease

, 2013
Copyright @ 2013 Janssens et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source
Janssens, L, Chris Burtin, Decramer, M., Burtin, C., Alison K McConnell, Janssens Lotte, Marc Decramer, McConnell Alison K., Lotte Janssens, Burtin, Chris, Claeys Kurt, Kurt Claeys, Brumagne, S, Janssens, W, Simon Brumagne, Janssens, Wim, Pijnenburg, M, Claeys, K., Troosters, T., McConnell, AK, Decramer Marc, Brumagne, Simon, Janssens, L., Madelon Pijnenburg, Claeys, Kurt, Pijnenburg, Madelon, Decramer, M, Wim Janssens, Janssens Wim, Claeys, K, Thierry Troosters, Troosters, T, Brumagne, S., McConnell, Alison K., Brumagne Simon, Decramer, Marc, Burtin, C, Pijnenburg, M., Janssens, W., Troosters Thierry, Pijnenburg Madelon, Troosters, Thierry, Janssens, Lotte, Burtin Chris   +43 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

HYDrodynamics with JETs (HYDJET++): Latest Developments and Results

Particles
Analysis of the (i) charge balance function and (ii) fluctuations of the net electric charge of hadrons in Pb+Pb collisions at center-of-mass energy 2.76 TeV per nucleon pair was performed within a two-component hydjet++ model.
Garnik Ambaryan, Larissa Bravina, Alexey Chernyshov, Gyulnara Eyyubova, Vladimir Korotkikh, Igor Lokhtin, Sergei Petrushanko, Alexandr Snigirev, Evgeny Zabrodin   +8 more
doaj   +1 more source