The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Balance Rehabilitation with Peripheral Visual Stimulation in Patients with Panic Disorder and Agoraphobia: An Open-Pilot Intervention Study. [PDF]
Caldirola D +5 more
europepmc +1 more source
Balance and Gait Rehabilitation in Patients with Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by cardinal features resting tremor, rigidity, bradykinesia, and postural difficulties which are thought to arise primarily from the loss of dopamine producing neurons and subsequent dysfunction of the basal ganglia-thalamo-cortical pathway (Konczak et al., 2009).
Smania N +6 more
openaire +3 more sources
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
Are Real-World Mobility Patterns Early Indicators of COPD Onset? Insights from Wrist-Worn Sensors
Nelida Fernandez,1 Arnold YL Wong,2 Matthew A Brodie,3 Kimberley S Van Schooten,4,5 Lloyd L Y Chan,4,6,* Stephen R Lord4,5,*1Department of Geriatrics, Getafe University Hospital, Madrid, Spain; 2Department of Rehabilitation Sciences, The ...
Fernandez N +5 more
doaj
Physical Activity Design for Balance Rehabilitation in Children with Autism Spectrum Disorder. [PDF]
Roșca AM +4 more
europepmc +1 more source
Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo +6 more
wiley +1 more source
Balance Rehabilitation Approach by Bobath and Vojta Methods in Cerebral Palsy: A Pilot Study. [PDF]
Ungureanu A, Rusu L, Rusu MR, Marin MI.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source

