Results 171 to 180 of about 12,678,772 (329)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Possible impacts of the transformation of water infrastructure on productive water uses: The case of the Seokodibeng village in South Africa [PDF]
Water users’ associations / Water supply / Social participation / Land use / Water use / Villages / History / Domestic water / Irrigation water / Food security / Sanitation / Cost recovery / Project management / Pipes / Water balance ...
Faysse, Nicolas +4 more
core
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
The social balance sheet 2005 [PDF]
Each year, the National Bank examines the provisional results of the social balance sheets of Belgian enterprises. As the social balance sheets are not yet all available for 2005, the study is based on a limited population of enterprises, compiled ...
P. Heuse, Ph. Delhez
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
The Purpose and Limits of Social Health Insurance [PDF]
This contribution seeks to answer two related questions. First, what is the purpose of social health insurance? Or put in slightly different terms, what are the reasons for social (or public) health insurance to exist, even to dominate private health ...
Peter Zweifel
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Balancing Wellbeing and Social Harmony
Authentic Development has been described in terms of substantial and balanced contributions of social harmony and wellbeing. Whereas objective indicators of wellbeing may be elaborated using the approaches of economists, objective indicators of social harmony are extremely difficult to define due to the exceedingly number of interdependent variables ...
Alberto Ciferri, Cinzia Bongianni
openaire +1 more source