Results 51 to 60 of about 422,290 (218)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ukraine’s Accession to the WTO: Strategy and Impediments [PDF]

open access: yesInternational Economic Policy, 2005
This paper focuses on issues surrounding Ukraine’s internal efforts for WTO accession given the importance of completing the negotiation process prior to the December 2005 Hong Kong Ministerial Conference.
Serhiy Lakhno
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Investment risk – management of the transnational corporations: paradigm of the ХХІ century [PDF]

open access: yesInternational Economic Policy, 2009
The article reveals the management conceptual frameworks of the international investment risks of transnational corporations in the current conditions. Since the operation models of the investments risks used in the practices of international management ...
Yevhen Panchenko, Maryna Damaskina
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Economic Imperative of Global Community Establishment [PDF]

open access: yesInternational Economic Policy, 2017
Modern global society is becoming increasingly controversial. Under such conditions, the question of prospects for life of megasociety, which demands theoretical and methodological research from the economic science, as well as a thorough analysis of ...
Deyneka Tatyana
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Strategies of the oil-and-gas TNC on the global investment market [PDF]

open access: yesInternational Economic Policy, 2011
There were studied theoretical and practical aspects of the formation and efficient implementation of corporate investment strategies in the global business environment.
Oleh Shvydkyi, Iryna Dzebykh
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Ukraine’s priorities in developing innovation in the context of eurointegrative processes [PDF]

open access: yesInternational Economic Policy, 2007
In the article the author substantiates the need to pursue more energetically international innovative activity to raise the competitiveness of the national economy.
Lesia Lyskova
doaj  

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