Results 51 to 60 of about 530,973 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Energy balance related behaviour: personal, home- and friend-related factors among schoolchildren in Europe studied in the ENERGY-project [PDF]

open access: yes, 2014
To design interventions that target energy balance-related behaviours, knowledge of primary schoolchildren's perceptions regarding soft drink intake, fruit juice intake, breakfast consumption, TV viewing and physical activity (PA) is essential.
Vik, Froydis N.   +48 more
core   +1 more source

Spatial navigation entropy suggests allocentric dysfunction in PPPD

open access: yesFrontiers in Neurology
IntroductionPersistent postural-perceptual dizziness (PPPD) is a common chronic dizziness disorder with an unclear pathophysiology. It is hypothesized that PPPD may involve functional dysfunction of the construction of inner cognitive maps, leading to ...
Felipe Faúndez   +13 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mercadeo social, responsabilidad socialy balance social: conceptos a desarrollar por instituciones universitarias

open access: yesTelos: Revista de Estudios Interdisciplinarios en Ciencias Sociales, 2010
Partiendo de diversas definiciones sobre mercadeo social, responsabilidad social y balance social a través de los autores: Pérez (2004); Guédez (2006) y Fernández et al.
Miguel Rendueles Mata
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Validation and Reliability Testing of the Yonsei Lifestyle Profile for Assessing Multifaceted Health Lifestyles

open access: yesHealth Care Science
Background In this study, we aimed to validate and test the reliability of the Yonsei lifestyle profile (YLP) in assessing multifaceted health lifestyle levels in a study population from the United States.
Young‐Myoung Lim   +3 more
doaj   +1 more source

Practical tips by peer support in chronic vestibular hypofunction: an exploratory survey

open access: yesFrontiers in Neurology
IntroductionPatients with chronic vestibular hypofunction typically suffer from dizziness, imbalance and oscillopsia (blurred vision); symptoms that pose challenges to everyday life.
Bernd Lode Vermorken   +5 more
doaj   +1 more source

The Development Round: Main Outcomes, Challenges and Implementation Prospects [PDF]

open access: yesInternational Economic Policy, 2004
The article touches upon current issues in the development of a WTO-based multilateral trade system and the participation of the broadest possible range of nations in this system, with special attention to the agenda of the Fourth and Fifth Ministerial ...
Volomymyr Vashchenko   +1 more
doaj  

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