Results 51 to 60 of about 422,290 (218)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ukraine’s Accession to the WTO: Strategy and Impediments [PDF]
This paper focuses on issues surrounding Ukraine’s internal efforts for WTO accession given the importance of completing the negotiation process prior to the December 2005 Hong Kong Ministerial Conference.
Serhiy Lakhno
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Investment risk – management of the transnational corporations: paradigm of the ХХІ century [PDF]
The article reveals the management conceptual frameworks of the international investment risks of transnational corporations in the current conditions. Since the operation models of the investments risks used in the practices of international management ...
Yevhen Panchenko, Maryna Damaskina
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Economic Imperative of Global Community Establishment [PDF]
Modern global society is becoming increasingly controversial. Under such conditions, the question of prospects for life of megasociety, which demands theoretical and methodological research from the economic science, as well as a thorough analysis of ...
Deyneka Tatyana
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Strategies of the oil-and-gas TNC on the global investment market [PDF]
There were studied theoretical and practical aspects of the formation and efficient implementation of corporate investment strategies in the global business environment.
Oleh Shvydkyi, Iryna Dzebykh
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ukraine’s priorities in developing innovation in the context of eurointegrative processes [PDF]
In the article the author substantiates the need to pursue more energetically international innovative activity to raise the competitiveness of the national economy.
Lesia Lyskova
doaj

