Results 101 to 110 of about 7,214,680 (253)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Social Balance Theory: Revisiting Heider’s Balance Theory for many agents
We construct a model based on Heider’s social balance theory to analyze the interpersonal network among social agents. The model of social balance theory provides us an interesting tool to see how a social group evolves to the possible balance state.
Situngkir, Mr Hokky, Khanafiah, Mr Deni
core
Non-classical continuum theories for solid and fluent continua and some applications
This paper presents two specific thermodynamically consistent non-classical continuum theories for solid and fluent continua. The first non-classical continuum theory for solid continua incorporates Jacobian of deformation in its entirety in the ...
K.S. Surana, D. Mysore, J.N. Reddy
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Aliance Behavior of States in Balance of Power Theory
This paper analyses the role of weak states in the theory of balance of power. Using advanced quantitative methods, this study builds on Stephan Walt’s concept of balance of threat, which is derived from an original theory of Kenneth Waltz, and examines
Maroš Lauer
doaj
Two-stage reciprocating small oil-free air compressors have been widely used in various fields due to their high exhaust pressure and low power consumption, but the vibration and noise problems seriously affect the comfort of use. In order to improve the
LIU JiaCheng +5 more
doaj
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Developing A Theory Of Board Strategic Balance 1
Developing A Theory Of Board Strategic Balance
David Shilbury (13094466) +1 more
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source

