Results 91 to 100 of about 7,931,824 (332)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
MICRONUTRIENT DEFICIENCIES IN CHILDREN OF PRESCHOOL AGE
Вопросы современной педиатрии, 2014 For the harmonious development of the child in early and preschool age diet should be balanced not only for proteins, fats and carbohydrates, but also include a sufficient amount of vitamins, trace elements and minerals.
I. N. Zakharova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Nutrition intake for smooth milk production in breastfeeding mother
JKS (Jurnal Kedokteran Syiah Kuala)Introduction: Nutrition is an organism's process of using food that is normally consumed through the process of digestion, absorption, transportation, storage, metabolism and excretion of substances that are not used to maintain life, growth and normal ...
Husnah Husnah
doaj +1 more source
Indeterminacy in a Two-sector Endogenous Growth Model with Productive Government Spending [PDF]
We extend the Barro (1990) model of endogenous growth to a two-sector one which consists of pure consumption and investment goods. It is possible that the extended version has a unique balanced growth rate such that for given initial values of state ...
Koji Shimomura, Ryoji Ohdoi, Yunfang Hu
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Fundamental Duality Theorem of Balanced Growth [PDF]
In this paper we demonstrate that a simple duality relation underlies balanced growth models with non-joint production. Included in this class of models is the standard neoclassical growth model and endogenous growth models that admit balanced growth ...
Don Ferguson, Ian King
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The effects of unionization in an R&D growth model with (In)determinate equilibrium [PDF]
This paper extends an R&D-based growth model of the Rivera-Batiz and Romer-type [Quarterly Journal of Economics 106 (1991) 531] endogenous growth model by embodying a union with elastic labor to investigate the effects of unionization on employment and ...
Lai, Chung-Hui, Wang, Vey
core +1 more source