Results 61 to 70 of about 1,369,077 (299)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
SystemsThis study examines how ambidextrous balanced innovation and ambidextrous combined innovation affect international entrepreneurial-oriented enterprise growth within the holistic paradigm of systems thinking and discusses the systemic impact of industry ...
Jinshan Zhang +2 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Balanced Scorecard Sebagai Alternatif Tool Sistem Manajemen Sekolah Abad 21
Tadbir: Jurnal Studi Manajemen Pendidikan, 2020 This paper aims to analyze the balanced scorecard as an alternative tool for school management systems in the 21st century as it is today. This research uses a qualitative approach with descriptive analysis.
Miftahul Huda, Rhoni Rodin
doaj +1 more source
Productive Efficiency in 16 European Countries [PDF]
We investigate in this paper differences in productive efficiency across sixteen European countries. In order to assess differences in productive efficiency, we have built a dynamic input-output model and computed for each country the balanced growth ...
Dino Martellato, Miguel A. Tarancón
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Feasibility of Balanced Scorecard Implementation in Performance Measurement of Shiraz Hospitals [PDF]
مطالعات تجربی حسابداری مالی, 2010 This study aims at investigating the feasibility of the application of "Balanced Scorecard", in performance measurement of Shiraz hospitals. Balanced Scorecard is one of the management accounting techniques which was first introduced by Robert Kaplan and
Sh. Khajavi, M. Sayrani, A. Allahyari
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
THE SOLOW¡¯S MODEL WITH ENDOGENOUS POPULATION: A NEOCLASSICAL GROWTH CYCLE MODEL [PDF]
It is shown here that the Solow (1956) neo-classical growth paradigm not only explains the ¡°first¡± stylised fact of economic growth, namely the existence of a globally stable state of balanced growth, but, once endowed with a demographically founded ...
Luciano Fanti, Piero Manfredi
core