Results 231 to 240 of about 86,443 (297)

Deep phenotyping of patient lived experience in functional bowel disorders using machine learning. [PDF]

Sci Rep
Ruffle JK, Henderson M, Ng CE, Liddle T, Nelson APK, Nachev P, Knowles CH, Yiannakou Y.   +7 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Mechanical needle guidance for ultrasound-guided parasagittal oblique in-plane paravertebral blocks: a cadaveric study. [PDF]

Braz J Anesthesiol
Elsharkawy H, Altinpulluk EY, Shimada T, Ince I, Mao G, Mas D Alessandro NM, Soliman LM, Harsha N, Kelava M, Drake R, Pu X, Sessler DI, Turan A.   +12 more
europepmc   +1 more source

Partially Balanced Incomplete Block Designs

, 2005
openaire   +2 more sources

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Bio-Inspired Neural Network Dynamics-Aware Reinforcement Learning for Spiking Neural Network. [PDF]

Biomimetics (Basel)
Zheng Y, Xue J, Yang J, Zhang Y.
europepmc   +1 more source

New Diallel Cross Designs Through Resolvable Balanced Incomplete Block Designs for Field Experiments

, 2018
Ijaz Iqbal, Maqsooda Parveen, Zafar Mahmood   +2 more
openalex   +1 more source

Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications

Advanced Science, EarlyView.
This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss, Vasiliki Gkouzioti, Wuliji Hanggai, Friso Kahler, Elena Aprea, Qi Jia, Jean‐Philippe Frimat, Ekkes Brück, Clementine M. Boutry   +8 more
wiley   +1 more source

Safety and efficacy of ultrasound-guided distal forearm median nerve block for pediatric trigger thumb release: a retrospective observational study in a southern Chinese cohort. [PDF]

Front Med (Lausanne)
Wang XX, Xu WC, Fang TF, Zhao ZH, Lin KN, Chen H.   +5 more
europepmc   +1 more source

INADMISSIBILITY OF TRUNCATED ESTIMATORS IN BALANCED INCOMPLETE BLOCK DESIGNS

, 1988
Tatsuya Kubokawa
openalex   +2 more sources