Results 31 to 40 of about 1,211,632 (235)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
CONSTRUCTION METHOD OF A-OPTIMAL CHEMICAL BALANCE WEIGHING DESIGNS
Acta Universitatis Lodziensis. Folia Oeconomica, 2015 Here, we study the design in that we determine unknown measurements of p objects by used of n measurement operations. For that reason we consider the chemical balance weighing design under assumption that the measurement errors are uncorrelated and they ...
Bronisław Ceranka, Małgorzata Graczyk
doaj
Symmetric balanced ternary designs with ϱ1 = 1 or 2
Aequationes Mathematicae, 1994 A balanced ternary design is a collection of blocks containing various points 0, 1 or 2 times and such that the size of the blocks and the number of occurrences of any point or any pair of distinct points simultaneously in the same block are constants.
openaire +2 more sources
On Variance Balanced Designs [PDF]
, 2017 Balanced incomplete block designs are not always possible to construct because of their parametric relations. In such a situation another balanced design, the variance balanced design, is required.
Dilip Kumar Ghosh +3 more
core +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Some constructions of nested balanced equireplicate block designs [PDF]
, 2003 arious methods of constructing nested ternary and quaternary efficiency balanced and variance balanced designs are proposed by applying some repetitions of treatments in all possible pairs of treatments.
Rai, Shivani +2 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Fast Addition Using Balanced Ternary Counters Designed with CMOS Semi-Floating Gate Devices [PDF]
37th International Symposium on Multiple-Valued Logic (ISMVL'07), 2007 This paper presents ternary counters using balanced ternary notation. The balanced ternary counters can replace binary full adders or counters in fast adder structures. The circuits use recharged CMOS semi-floating gate (RSFG) devices. By using balanced ternary notation, it is possible to build balanced ternary addition circuits, which can add both ...
Henning Gundersen, Yngvar Berg
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On the study of balanced incomplete block designs with repeated blocks and other incomplete block designs [PDF]
, 2004 Not ...
Sharma, Rajeshkumar
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source