Results 141 to 150 of about 774,968 (312)

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

Live birth from a patient with a threeway balanced translocation t5 8 12

South African Journal of Obstetrics and Gynaecology, 2015
Background: Three-way balanced translocations are unusual and can lead to infertility as well as abnormal embryos. In this case report we describe a couple that experienced repeated miscarriages due to the male partner being a carrier of a three-way ...
Anil Ramdeo, Kinnon Naidoo, Teresa Ernest, Katarzyna Pluta   +3 more
doaj   +1 more source

Balanced Translocation Disrupting <i>JAG1</i> Identified by Optical Genomic Mapping in Suspected Alagille Syndrome. [PDF]

Hum Mutat, 2023
Zhang YQ, Gao PF, Yang JM, Zhang J, Lu YL, Wang JS.   +5 more
europepmc   +1 more source

Partial trisomy 16q21➔qter due to an unbalanced segregation of a maternally inherited balanced translocation 46,XX,t(15;16)(p13;q21): a case report and review of literature [PDF]

, 2018
Rupesh Mishra, C. S. Paththinige, Nirmala D. Sirisena, S. Nanayakkara, U. G. I. U. Kariyawasam, Vajira H. W. Dissanayake   +5 more
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Gene sequencing and result analysis of balanced translocation carriers by third-generation gene sequencing technology. [PDF]

Sci Rep, 2023
Zeng X, Lin D, Liang D, Huang J, Yi J, Lin D, Zhang Z.   +6 more
europepmc   +1 more source

A fetus with an X;1 balanced reciprocal translocation and eye disease. [PDF]

, 1995
Mary J. Seller, K. PAL, Sharon W. Horsley, Angela Davies, Andrew C. Berry, R Meredith, A C McCartney   +6 more
openalex   +1 more source

Rapid Glass‐Substrate Digital Light 3D Printing Enables Anatomically Accurate Stroke Patient‐Specific Carotid Artery‐on‐Chips for Personalized Thrombosis Investigation

Advanced Materials, EarlyView.
A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao, Zihao Wang, Arian Nasser, Allan Sun, Zhao Wang, Yingqi Zhang, Jianfang Ren, Haimei Zhao, Nicole Alexis Yap, Yinyan Wang, Zhiyong Li, Ken S Butcher, Freda Passam, Timothy Ang, Lining Arnold Ju   +14 more
wiley   +1 more source

A Rare 46,X,t(Y;10)(q12;p14) Balanced Translocation in Non-Obstructive Azoospermic Patient with Elevated FSH and LH Levels. [PDF]

Case Rep Genet, 2023
Jahan Syeeda Khursheed K, Rahman Kaleemullah M, Joseph A, Hasan Al Durazi M, Bakhiet M.   +4 more
europepmc   +1 more source

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

Advanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad, Ahmad Amiri, Maik Böhmer, Soofia Khanahmadi   +3 more
wiley   +1 more source