Results 271 to 280 of about 105,723 (318)

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Ionic Highways under Multivariate‐Coupled Strategies: Ultrahigh Power Generation from Industrial Waste Liquors Using Robust COF Membranes

Advanced Science, EarlyView.
This study presents a multivariate‐coupled strategy to fabricate TB‐COF membranes with tunable charge density via uniformly distributed Bpy groups, enabling efficient ion transport and energy harvesting. The robust β‐ketoenamine‐linked structure ensures stability, achieving power outputs of 53.08 W m−2 (pH 4), 190.52 W m−2 (low‐grade heat), and 258.81 ...
Hongyan Qi, Weibo Sun, Jundong Zhong, Zhen Xing, Tingting Xu, Shuang Zhao, Haoyang Tan, Ziyi Hu, Hujun Qian, Yuchen Wu, Haibo Zhang, Jianxin Mu, Xuanbo Zhu, Lei Jiang   +13 more
wiley   +1 more source

Wearable Thermoelectric Generators for In Vivo Modulation of Insulin Release

Advanced Energy Materials, EarlyView.
This work presents a wearable, self‐powered thermoelectric system (IGNITE) that sustainably harvests body heat to electrically stimulate engineered human cells for insulin release. Operating autonomously without batteries, IGNITE achieves glycemic control in diabetic mice, demonstrating a significant advance in bioelectronic medicine and setting the ...
Debasis Maity, Jinbo Huang, Martin Fussenegger   +2 more
wiley   +1 more source

Breakpoint-resolved balanced t(2;12)(q35;q24.31) disrupting <i>HNF1A</i> in multigenerational MODY-3: Diagnostic utility of long-read genome sequencing and therapeutic impact. [PDF]

Metabol Open
Rivero-García P, Mutchinick OM, Huerta-Ávila E, Colorado IA, Alfonso-López C, Rivera-Juárez R, Santiago-Cano V, Morales-Suárez JJ, Hidalgo-Miranda A, Svyryd Y.   +9 more
europepmc   +1 more source

A Phenotypically Normal Homozygous Balanced Reciprocal Translocation Carrier: Report of an Extremely Rare Genetic Occurrence. [PDF]

Cureus
Thirupathy M, Shetty M, Prakash P.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Disomic balanced reciprocal translocation

Clinical Genetics, 1990
The previously unreported and unique finding of a complete disomy of an apparently balanced reciprocal translocation is described. The parents are second cousins once removed and each parent contributed the same balanced reciprocal translocation chromosome. Although the complete disomy involves balanced translocation chromosomes from unaffected parents,
P L, Wilmot, L R, Shapiro, A C, Casamassima   +2 more
openaire   +2 more sources

Balanced translocations in mental retardation

Human Genetics, 2009
Over the past few decades, the knowledge on genetic defects causing mental retardation has dramatically increased. In this review, we discuss the importance of balanced chromosomal translocations in the identification of genes responsible for mental retardation.
Vandeweyer, Geert, Kooy, Frank
openaire   +3 more sources

Balanced autosomal translocations and ovarian dysgenesis

Human Genetics, 1994
We report two unrelated women with gonadal dysgenesis, and a (6;15)(p21.3;q15) and a (8;9)(p11.2;q12) balanced translocation, respectively. The patients were of normal stature and showed no phenotypic abnormality or malformation other than ovarian failure.
TUPLER, Rossella, L. BARBIERATO, D. LARIZZA, P. SAMPAOLO, F. PIOVELLA, P. MARASCHIO   +5 more
openaire   +3 more sources