Results 61 to 70 of about 57,297 (238)

Cryptic subtelomeric rearrangements and X chromosome mosaicism: a study of 565 apparently normal individuals with fluorescent in situ hybridization. [PDF]

PLoS ONE, 2009
Five percent of patients with unexplained mental retardation have been attributed to cryptic unbalanced subtelomeric rearrangements. Half of these affected individuals have inherited the rearrangement from a parent who is a carrier for a balanced ...
Jasen L Wise, Richard J Crout, Daniel W McNeil, Robert J Weyant, Mary L Marazita, Sharon L Wenger   +5 more
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Efficacy of Probiotics for Reducing the Incidence of Lameness in Broilers Grown on Wire Flooring [PDF]

, 2013
Growing broilers on wire flooring provides an excellent experimental model for reproducibly triggering significant levels of lameness. In Pilot Study #1 using broilers from Line C grown on wire flooring, adding the Biomin probiotic PoultryStar® to the ...
Stark, John Matthew
core   +2 more sources

Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]

, 2014
Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna, Avner, Balderas-Renteria, Bray, Chan, Cho, Cho, Cragg, Cragg, Dawson, Dennison, Dennison, Dennison, Dennison, Gaspar, Gotay, Harris, Harris, Harris, Harris, Harris, Hess, Hogberg, Khazir, Li, Lumb, Malde, Mandal, Mandal, Martin Sabroso, Newman, Nicolas, Oh, Pasupuleti, Phoenix, Phoenix, Phoenix, Phoenix, Prabhu, Prabhu, Rajanbabu, Riedl, Saraswathy, Shekhar, Song, Tsuda, Unnati, Urruticoechea, Van der Spoel, Varadhachary, Wall, Wang, Wang, Whitmore, Whitmore, Whitmore, Yeung   +56 more
core   +1 more source

The decision on the embryo to transfer after Preimplantation Genetic Diagnosis for X-autosome reciprocal translocation in male carrier

Molecular Cytogenetics, 2018
Background The aim of Preimplantation Genetic Diagnosis (PGD) on embryos produced in vitro is to identify the embryos without genetic or chromosomal defect from those embryos that will develop the genetic disease or are chromosomally abnormal. In case of
Sandrine Chamayou, Maria Sicali, Debora Lombardo, Carmelita Alecci, Antonino Guglielmino   +4 more
doaj   +1 more source

Analysis of clinical outcomes and meiotic segregation modes following preimplantation genetic testing for structural rearrangements using aCGH/NGS in couples with balanced chromosome rearrangement

Reproductive Medicine and Biology, 2022
Purpose To retrospectively evaluate the effectiveness of PGT‐SR by array comparative genomic hybridization (aCGH) or next‐generation sequencing (NGS) in preventing recurrent miscarriages.
Tatsuya Nakano, Michiko Ammae, Manabu Satoh, Satoshi Mizuno, Yoshiharu Nakaoka, Yoshiharu Morimoto   +5 more
doaj   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Characterization of a rare analphoid supernumerary marker chromosome in mosaic [PDF]

, 2015
publicado em: Chromosome Research. 2015;23(Suppl 1):67-8. doi:10.1007/s10577-015-9476-6Analphoid supernumerary marker chromosomes (SMCs) are a rare subclass of SMCs C-band-negative and devoid of alpha-satellite DNA.
Alves, C., Amorim, M., Brito, F., Correia, H., Ferreira, C., Marques, B., Pedro, S.   +6 more
core  

Catastrophic chromosomal restructuring during genome elimination in plants. [PDF]

, 2015
Genome instability is associated with mitotic errors and cancer. This phenomenon can lead to deleterious rearrangements, but also genetic novelty, and many questions regarding its genesis, fate and evolutionary role remain unanswered.
Bradnam, Keith R, Chan, Simon Wl, Comai, Luca, Henry, Isabelle M, Korf, Ian, Lysak, Martin A, Mandakova, Terezie, Marimuthu, Mohan Pa, Ravi, Maruthachalam, Tan, Ek Han   +9 more
core   +1 more source

A feasible diagnostic approach for the translocation carrier from the indication of products of conception

Molecular Cytogenetics, 2018
Background Chromosome translocations are rare but frequently associated with infertility. The objective of this study is to investigate the feasibility of using chromosomal microarray analysis (CMA) on products of conception (POC) samples as an indicator
Ye-Qing Qian, Xiao-Ying Fu, Xiao-Qing Wang, Yu-Qin Luo, Min Chen, Kai Yan, Yan-Mei Yang, Bei Liu, Li-Ya Wang, Ying-Zhi Huang, Hong-Ge Li, Hang-Yi Pan, Fan Jin, Min-Yue Dong   +13 more
doaj   +1 more source