Results 101 to 110 of about 9,084,007 (293)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
MathematicsDisassembly line balancing (DLB) is a crucial optimization item in the recycling and remanufacturing of waste products. Considering the variations in the number of operators assigned to each station, this study investigates DLBs with six distinct station
Tao Yin +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An Institutional Frame to Compare Alternative Market Designs in EU Electricity Balancing [PDF]
, 2006 The so-called â electricity wholesale marketâ is, in fact, a sequence of several markets. The chain is closed with a provision for â balancing,â in which energy from all wholesale markets is balanced under the authority of the Transmission Grid ...
Marcelo Saguan +3 more
core +2 more sources
A fast algorithm for matrix balancing [PDF]
, 2013 As long as a square nonnegative matrix A contains sufficient nonzero elements, then the matrix can be balanced, that is we can find a diagonal scaling of A that is doubly stochastic. A number of algorithms have been proposed to achieve the balancing, the
Knight, Philip, Ruiz, Daniel
core +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A Simulated Annealing Method to Cover Dynamic Load Balancing in Grid Environment [PDF]
, 2009 High-performance scheduling is critical to the achievement of application performance on the computational grid. New scheduling algorithms are in demand for addressing new concerns arising in the grid environment.
Herrero Martín, María del Pilar +1 more
core +1 more source
Flexible Multi-Battery System With Active Balancing and Voltage Regulation
IEEE AccessThis paper presents a flexible multi-battery system with active balancing and voltage regulation. The presented battery system has two main features: (1) active balancing can be achieved between batteries connected in series/parallel using a balancing ...
Mohammad K. Al-Smadi +1 more
doaj +1 more source
Journal of Big Data, 2020 MapReduce is used within the Hadoop framework, which handles two important tasks: mapping and reducing. Data clustering in mappers and reducers can decrease the execution time, as similar data can be assigned to the same reducer with one key.
Ali Bakhthemmat, Mohammad Izadi
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source