Results 161 to 170 of about 219,325 (264)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Divergent cis-regulatory haplotypes at Tlr2 are associated with immune responsiveness. [PDF]

Mol Biol Evol
Nandakumar M, Lundberg M, Nouri M, Valfridsson C, Carlsson F, Råberg L.   +5 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

A systems approach to understanding injury care in LMICs using causal loop diagrams. [PDF]

BMJ Glob Health
Davies JI, Chu K, D'Ambruoso L, Bojke L, English R, Geduld H, Lahri S, Mahomed H, Matzopoulos R, Tako AA.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Overdominance for fitness: a genomic comparison between empirical and simulated data with Drosophila melanogaster. [PDF]

Genetics
González-Castellano I, Quesada H, Ramos-Onsins S, García-Dorado A, Caballero A.   +4 more
europepmc   +1 more source

Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley   +1 more source

Structural analysis and causal loop modelling: an integrated systems approach to analysing perinatal service delivery in carceral settings in Ontario, Canada. [PDF]

Health Res Policy Syst
Bancroft X, McGee A, Morgan L, Ferron Parayre A, Peterson WE.   +4 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Genetic Diversification and Population Admixture Signatures in Yunnan Native Cattle. [PDF]

Animals (Basel)
Liu Y, Dao W, Xu W, Fan X, Yang R, Miao Y.   +5 more
europepmc   +1 more source