Results 101 to 110 of about 1,555,880 (294)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Generalization of Gaussian Balancing and Gaussian Balancing-Lucas Numbers With Applications

open access: yesInternational Journal of Mathematics and Mathematical Sciences
In this paper, we study a generalization of Gaussian balancing and Gaussian Lucas-balancing numbers, we find their generating functions, Binet formulas, related matrix representation, and many other properties.
T. Al-Asoully, A. Al-Kateeb
doaj   +1 more source

On $${\pmb k}$$-Fibonacci numbers expressible as product of two Balancing or Lucas-Balancing numbers

open access: yesIndian Journal of Pure and Applied Mathematics, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

On the Existence of Solutions of Diophantine Equations Related to Subbalancing Numbers

open access: yesJournal of Mathematics
In this paper, we introduce a new sequence of subbalancing numbers by considering balancing numbers as the values of D in the Diophantine equations provided by subbalancing numbers.
Selin Sarı, Gül Karadeniz-Gözeri
doaj   +1 more source

No detrimental effect of ligament balancing on functional outcome after total knee arthroplasty: a prospective cohort study on 129 mechanically aligned knees with 3 years’ follow-up

open access: yesActa Orthopaedica, 2018
Background and purpose — In the classical mechanical alignment technique, ligament balancing is considered a prerequisite for good function and endurance in total knee arthroplasty (TKA).
Eirik Aunan, Stephan M Röhrl
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Generalized balancing numbers [PDF]

open access: yes, 2017
Bu çalışmada tamsayı dizilerinde yeni bir kavram olan t −balans sayıları ele alınmış ve bu sayıların bazı cebirsel özellikleri verilmiştir. Ayrıca bu sayıların Pell, Pell-Lucas, diğer balans sayıları ve kare üçgensel sayılar ile olan ilişkisinden ...
Yazla, Aziz
core  

On non-Newtonian balancing type numbers [PDF]

open access: yes
In this paper, we introduce non-Newtonian balancing type numbers. In non-Newtonian calculus, we examine formulas and identities for classical balancing numbers. We give Binet-type formula for non-Newtonian balancing numbers and the general bilinear index-
Szynal-Liana, Anetta
core   +1 more source

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