Results 171 to 180 of about 429,871 (281)

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

Predicting Coronary Occlusion Risk during Redo‐TAVR at First TAVR: Asymmetric Calcification Causes Failure

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Predicting coronary artery occlusion due to sinus sequestration (SS) during a second transcatheter aortic valve (TAV) procedure using pre‐procedural computed tomography (CT) after the first TAV replacement (TAVR) is underreported.
Kyohei Onishi   +12 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

open access: yesHepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol   +22 more
wiley   +1 more source

Intra‐Annular Versus Supra‐Annular Self‐Expanding Valves for Valve‐in‐Valve TAVR

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background A limitation of Valve‐in‐Valve (VIV) transcatheter aortic valve replacement (TAVR) is patient‐prosthesis mismatch (PPM), which is associated with worse quality of life and heart failure hospitalizations. As such, strategies to avoid PPM are desired. We compared the clinical and hemodynamic results of VIV TAVR with intra‐annular self‐
John T. Saxon   +19 more
wiley   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro   +17 more
wiley   +1 more source

The Verification of Co‐Axiality of the Three Self‐Expanding Transcatheter Aortic Valve Systems According to the Difference in Shaft Spine

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Accurate bioprosthesis implantation depth during transcatheter aortic valve replacement (TAVR) is crucial for optimal outcomes. Self‐expanding valves (SEVs) have evolved delivery catheter designs, from a double spine shaft in Evolut PRO+ (PRO + ) to single spine in Evolut FX (FX) and non‐spine in Navitor, to improve access ...
Yun Teng   +13 more
wiley   +1 more source

Clinical Impact of Angiographic Complications Occurring During Percutaneous Coronary Interventions

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The clinical impact of different types of angiographic complications during elective PCIs remains largely unexplored. Aims To explore the incidence, management, and outcomes of angiographic complications by type and severity during non‐urgent, non‐CTO PCIs. Methods Clinical and procedural characteristics were prospectively collected
Emiliano Bianchini   +16 more
wiley   +1 more source

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