Results 291 to 300 of about 480,284 (338)

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren   +16 more
wiley   +1 more source

Novel Sulfur‐Containing Polyurethanes using 5‐(Chloromethyl)Furfural as a Renewable Building Block

open access: yesChemSusChem, EarlyView.
A novel methodology is presented for synthesizing biomass‐derived diols using 5‐(chloromethyl)furfural, thiols, and mild reaction conditions. These innovative diols are subsequently utilized in the production of new polyurethanes via polyaddition with both commercially available and biomass‐derived diisocyanates.
Jorge Andrés Mora Vargas   +5 more
wiley   +1 more source

A continuous 500‐year sediment record of inundation by local and distant tsunamis in South‐Central Chile (40.1°S)

open access: yesThe Depositional Record, EarlyView.
Tsunami events over the past 500 years inundated Laguna Gemela West (Chile), leading to distinct sandy deposits in the lake record. This provides a complete perspective on tsunami inundation, including giant tsunamis, small local tsunamis and tsunamis that originated >100 km away from the site.
Jasper Moernaut   +8 more
wiley   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa   +2 more
wiley   +1 more source

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel   +5 more
wiley   +1 more source

Development of a Novel, Pulmonary Endovascular Device to Treat Patients With Pulmonary Hypertension. [PDF]

open access: yesPulm Circ
Vollmers K   +8 more
europepmc   +1 more source

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