Results 31 to 40 of about 28,197 (262)

Comparative efficacy of different interventions for post-stroke cricopharyngeal achalasia: a systematic review and network meta-analysis

Frontiers in Neurology
ObjectiveThis study aims to employ network meta-analysis to systematically compare and evaluate the efficacy of various interventions for post-stroke cricopharyngeal achalasia.MethodsWe searched 10 databases and trial registries from inception to ...
Jianghuan Yue, Xiuli Wang, Cuiting Li, Lulu Wang, Xiaoling Li   +4 more
doaj   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Crease‐Encoded Soft Origami Chambers: A Unified Design‐to‐Fabrication Framework for Low‐Pressure Pneumatic Joints

Advanced Intelligent Systems, EarlyView.
Origami turns a single silicone chamber into three different soft fluidic actuators. Crease angles alone decide whether it elongates, bends, or twists, and the fully folded chambers are cast monolithically in one day. Below 15 kPa, they reach 268% axial stretch, 72° bending, and 55° twist—no strain‐limiting layers, no rigid reinforcements, no vacuum ...
Alexia Le Gall, Mattia Franchi de’ Cavalieri, Gastone Ciuti, Arianna Menciassi, Matteo Cianchetti   +4 more
wiley   +1 more source

Pre-dilation and Post-dilation in Transcatheter Aortic Valve Replacement: Indications, Benefits and Risks

Interventional Cardiology: Reviews, Research, Resources, 2021
Transcatheter aortic valve replacement (TAVR) is an established treatment for patients with symptomatic severe aortic stenosis. In recent years, an emphasis has been placed on simplification of the procedure.
Angela McInerney, Rafael Vera-Urquiza, Gabriela Tirado-Conte, Luis Marroquin, Pilar Jimenez-Quevedo, Iván Nuñez-Gil, Eduardo Pozo, Nieves Gonzalo, Jose Alberto de Agustín, Javier Escaned, Antonio Fernández-Ortiz, Carlos Macaya, Luis Nombela-Franco   +12 more
doaj   +1 more source

Artificial Intelligence for Benign Esophageal Stricture Dilation: An Evidence‐Transferability Framework and Safety‐First Roadmap

AI &Innovation, EarlyView.
ABSTRACT Background Endoscopic dilation is first‐line therapy for symptomatic benign esophageal strictures but remains operator‐dependent. Artificial intelligence (AI) could support assessment, risk stratification, and documentation; however, evidence from adjacent tasks is often mistaken for procedure‐specific validation.
Ahmed A. Salman, Mohamed A. Salman
wiley   +1 more source

Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway

Animal Models and Experimental Medicine, EarlyView.
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu, Chen Wang, Hui‐Min Tao, Jin Huang, Wei‐Qin Li, Zhi‐Ning Fan   +5 more
wiley   +1 more source

Outcomes of Holmium Laser, Cryoablation, and Budesonide Inhalation for Treating Severe Central Airway Stenosis in Infants

Journal of Investigative Surgery, 2023
Background Central airway stenosis (CAS) in infants is characterized by dysphonia, dyspnea, cyanosis, repeated apnea, and infection. This case series study aimed to evaluate the safety and efficacy of holmium laser, cryoablation and budesonide inhalation
Lei Zhang, Shuhua Yuan, Chunhong Pan, Jing Zhang, Jinhong Wu, Yong Yin   +5 more
doaj   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Successful Endoscopic Dilation Treatment of Small Intestinal Stricture Occurring during Chemotherapy for Malignant Lymphoma

Case Reports in Gastroenterology, 2010
We report a stricture occurring during chemotherapy for malignant lymphoma that was successfully treated by endoscopic balloon dilation. The patient was diagnosed with stage IV malignant lymphoma by esophagogastroduodenoscopy and computed tomography ...
Yusuke Honzawa, Masahiko Kondo, Takanobu Hayakumo, Minoru Matsuura, Hiroshi Nakase   +4 more
doaj   +1 more source