Results 161 to 170 of about 130,114 (271)

Integration of Membrane Proteins into the Outer Membrane of Diderm Bacteria by the BAM Complex. [PDF]

Chem Rev
Birtles D, Fenn KL, Machin JM, Radford SE, Ranson NA.   +4 more
europepmc   +1 more source

Molecular biology of the mouse Q region [PDF]

, 1987
A. Eastman O'Neill, A. Winoto, A.-M. Lew, A.L. Mellor, A.L. Mellor, A.L. Mellor, C. Jaulin, C.G. Miyada, D. Cosman, D. Cosman, D. Stephan, D.A. Fisher, D.H. Schulze, D.S. Straus, E.H. Weiss, E.H. Weiss, E.H. Weiss, Elisabeth H. Weiss, F. Bregegere, I. Stroynowski, J. Geliebter, J. Klein, J. Michaelson, J. Stroynowski, J.H. Rogers, J.H. Rogers, J.J. Devlin, J.J. Devlin, J.L. Lalanne, J.L. Lalanne, L. Flaherty, L. Flaherty, L.R. Pease, M. Kress, M. Steinmetz, M. Steinmetz, R.A. Flavell, R.A. Flavell, R.S. Goodenow, S.G. Nathenson, W.L. Maloy, Y. Obata   +41 more
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

A fluorescent reporter and single-turnover kinetics reveal insight into BAM complex function. [PDF]

Proc Natl Acad Sci U S A
Bergman WN, Sousa MC.
europepmc   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Native β-barrel substrates pass through two shared intermediates during folding on the BAM complex. [PDF]

Proc Natl Acad Sci U S A
Dos Santos TMA, Thomson BD, Marquez MD, Pan L, Monfared TH, Kahne DE.   +5 more
europepmc   +1 more source

Spatiotemporal topography of the BAM complex in relation to peptidoglycan and cell division

, 2022
Gram-negative bacteria possess a three-layered envelope composed of two concentric membranes, the inner membrane and the outer membrane (OM). In-between an aqueous space called the periplasm that contains the peptidoglycan (PG) layer. The envelope ensures protection against diverse hostile environments and offers an effective barrier against ...
openaire   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

A minimum functional form of the Escherichia coli BAM complex constituted by BamADE assembles outer membrane proteins in vitro. [PDF]

J Biol Chem
Wang Z, Chu Y, Li Q, Han X, Zhao L, Zhang H, Cai K, Zhang X, Wang X, Qin Y, Fan E.   +10 more
europepmc   +1 more source