Results 11 to 20 of about 54,185 (180)

Oxidized soluble guanylyl cyclase causes erectile dysfunction in alcoholic mice

open access: yesBritish Journal of Pharmacology, Volume 180, Issue 18, Page 2361-2376, September 2023., 2023
Background and purpose Alcohol abuse has been associated with erectile dysfunction (ED), but the implicated molecular mechanisms are unresolved. This study analyses the role of alterations in soluble guanylyl cyclase (sGC) in ED. Experimental approach ED was analysed in adult male C57BL/6J mice subjected to the Chronic Intermittent Ethanol (CIE ...
Miguel A. Olivencia   +8 more
wiley   +1 more source

New karyotype for Mesomys stimulax (Rodentia, Echimyidae) from the Brazilian Amazon: A case for species complex?

open access: yesEcology and Evolution, Volume 11, Issue 12, Page 7125-7131, June 2021., 2021
We studied the karyotype of Mesomys stimulax collected from the Amazon rainforest. The obtained karyotype (2n = 60 and FN = 110) differs from that described in the literature. These results suggest that M. stimulax may represent a complex of species and/or cryptic species.
Stella Miranda Malcher   +6 more
wiley   +1 more source

Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors

open access: yesMolecular Oncology, Volume 15, Issue 4, Page 846-865, April 2021., 2021
We report a study pipeline for exploring whether aberrant promoter methylation of genes involved in the homologous recombination pathway determines responsiveness to PARP inhibitors in testicular germ cell tumor patients. In silico analyses were followed by validation using quantitative methylation‐specific PCR.
João Lobo   +13 more
wiley   +1 more source

Molecular Mechanism for Protection Against Liver Failure in Human Yellow Fever Infection

open access: yesHepatology Communications, Volume 4, Issue 5, Page 657-669, May 2020., 2020
Yellow fever (YF) is a viral hemorrhagic fever that typically involves the liver. Brazil recently experienced its largest recorded YF outbreak, and the disease was fatal in more than a third of affected individuals, mostly because of acute liver failure.
Fernanda de Oliveira Lemos   +16 more
wiley   +1 more source

Search strategy in information retrieval : literature review [PDF]

open access: yes, 2002
Os sistemas de recuperação de informação, também denominados de bancos de dados, apresentam uma complexidade indiscutível no processo de armazenamento e busca da informação, envolvendo uma série de aspectos que são interdependentes.
Lopes, Ilza Leite
core   +2 more sources

DOAÇÃO DE LEITE MATERNO AO BANCO DE LEITE HUMANO: CONHECENDO A DOADORA

open access: yesDEMETRA: Alimentação, Nutrição & Saúde, 2015
Objetivo : Descrever o perfil das doadoras de leite humano ao Banco de Leite Humano de um hospital universitario do municipio de Cuiaba-MT. Metodo : Estudo observacional, de corte transversal realizado com todas as nutrizes cadastradas no Banco de Leite Humano como doadoras externas, utilizando questionario semiestruturado entregues as nutrizes ...
Emily Semenov Silva   +4 more
openaire   +2 more sources

Perfil calórico do leite pasteurizado no banco de leite humano de um hospital escola [PDF]

open access: yesRevista Paulista de Pediatria, 2013
OBJETIVO: Conhecer o perfil calórico e higiênico sanitário do leite humano do Banco de Leite Humano do Hospital Universitário de Londrina. MÉTODOS: Estudo quantitativo transversal do levantamento de dados obtidos de fontes secundárias de registros dos exames de teor calórico, avaliado pelo crematócrito, e da titulação de acidez pelo método de Dornic do
Moraes, Priscila Santa de   +2 more
openaire   +3 more sources

Controlled and natural language use in the databases : literature review [PDF]

open access: yes, 2002
O trabalho tem como objetivo examinar o uso da linguagem controlada ou da linguagem natural , no planejamento da estratégia de busca em um ambiente de bases de dados em CD-ROM ou em linha.
Lopes, Ilza Leite
core   +3 more sources

BANCO DE LEITE HUMANO: MULHERES COM DIFICULDADES NA LACTAÇÃO [PDF]

open access: yesCogitare Enfermagem, 2020
Objetivo: conhecer as dificuldades das mulheres que procuram atendimento no Banco de LeiteHumano.Método: trata-se de um estudo documental, retrospectivo, utilizando amostra de 292 formuláriosde puérperas que buscaram o serviço especializado do Banco de Leite Humano em HospitalUniversitário no Nordeste do Brasil.
Ana Paula Matos Ferreira   +6 more
openaire   +1 more source

A Bivalent Recombinant Mycobacterium bovis BCG Expressing the S1 Subunit of the Pertussis Toxin Induces a Polyfunctional CD4+ T Cell Immune Response

open access: yesBioMed Research International, Volume 2019, Issue 1, 2019., 2019
Background. A recombinant BCG strain expressing the genetically detoxified S1 subunit of pertussis toxin 9K/129G (rBCG‐S1PT), previously constructed by our research group, demonstrated the ability to develop high protection in mouse models of pertussis challenge which correlated with the induction of a Th1 immune response pattern.
Alex I. Kanno   +5 more
wiley   +1 more source

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