Results 131 to 140 of about 22,233,110 (357)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Anticuerpos naturales anti banda 3: Participan en el fenómeno de vasooclusión de la drepanocitosis Natural anti-band 3 antibodies: Do they take part in the phenomenon of vasoocclusion drepanocytosis

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2007
Se determinó la presencia de anticuerpos naturales anti banda 3 mediante un ensayo inmunoenzimático en microplacas acopladas con la proteína banda 3 en 14 pacientes con drepanocitosis, 4 con crisis vasooclusiva dolorosa y 10 en estado basal.
Rinaldo Villaescusa Blanco   +4 more
doaj  

Validation of a Novel, Rapid Sepsis Diagnostic for Emergency Department Use

open access: yesCritical Care Explorations
OBJECTIVES:. To assess the in vitro IntelliSep test, a microfluidic assay that quantifies the state of immune activation by evaluating the biophysical properties of leukocytes, as a rapid diagnostic for sepsis. DESIGN:. Prospective cohort study. SETTING:.
Hollis R. O’Neal, Jr, MD, MSc   +24 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Band 3 Protein: An Effective Interrogation Tool of Storage Lesions in RBC Units. [PDF]

open access: yesIndian J Hematol Blood Transfus, 2022
Ameri Z   +6 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Mercury Chloride Affects Band 3 Protein-Mediated Anionic Transport in Red Blood Cells: Role of Oxidative Stress and Protective Effect of Olive Oil Polyphenols. [PDF]

open access: yesCells, 2023
Perrone P   +10 more
europepmc   +1 more source

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