Results 151 to 160 of about 22,233,110 (357)

Gott und die Welt. Religiöse Vorstellungen des frühen und hohen Mittelalters. Teil I, Band 3 [PDF]

, 2016
Hans−Werner Goetz
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Crystal structure of the anion exchanger domain of human erythrocyte band 3

Science, 2015
T. Arakawa, Takami Kobayashi-Yurugi, Y. Alguel, H. Iwanari, Hinako Hatae, M. Iwata, Y. Abe, T. Hino, Chiyo Ikeda-Suno, H. Kuma, D. Kang, T. Murata, T. Hamakubo, A. Cameron, Takuya Kobayashi, N. Hamasaki, S. Iwata   +16 more
semanticscholar   +1 more source

Reduction in Gap State Density near Valence Band Edge at Al₂O₃/p‐type GaN Interface by Photoelectrochemical Etching and Subsequent SiO₂ Cap Annealing [PDF]

Yining Jiao, Takahide Nukariya, Umi Takatsu, Tetsuo Narita, Tetsu Kachi, Taketomo Sato, Masamichi Akazawa   +6 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The Human Intron-Containing Gene for Glycogenin Maps to Chromosome 3, Band q24

, 1996
Joseph Lomako, Krzysztof Mazuruk, Wieslawa M. Lomako, Miriam Alonso, William J. Whelan, Ignacio R. Rodríguez   +5 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

P-OS3-3 Pulse wave sensor like a Band-Aid for measuring pulse wave velocity

, 2012
Akihiro Michikawa, Yuu Osaki, Tetsuji DOHI   +2 more
openalex   +2 more sources