Results 151 to 160 of about 171,744 (267)

Pylluminator: fast and scalable analysis of DNA methylation data in Python. [PDF]

Bioinform Adv
Fanchon E, Loire B, Trani JP, Magdinier F, Baudot A.   +4 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Visible-light photocatalytic water splitting performance of V and Co codoped SrTiO₃: a first-principles study. [PDF]

RSC Adv
Li C, Qiu J, Wen J, Luo X.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

A Novel Mechanism of Optical Spectrum Formation in the Cs₂NaInCl₆ Doped with Sb and Er. [PDF]

Chem Mater
Ivashchenko IA, Makowska-Janusik M, Gulay LD, Kazarinov YG, Lamonova KV, Smortsova Y, Popov AI, Matras-Postołek K.   +7 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

DSKO: Dancing through DFTB Parametrization. [PDF]

J Chem Theory Comput
Samtsevych A, Song Y, van der Heide T, Aradi B, Hourahine B, Maurer RJ, Reuter K, Scheurer C, Panosetti C.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Enhanced climbing image nudged elastic band method with Hessian eigenmode alignment. [PDF]

Front Chem
Goswami R, Gunde M, Jónsson H.
europepmc   +1 more source