Results 41 to 50 of about 97,993 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Efficient Algorithm to Design Nearly Perfect-Reconstruction Two-Channel Quadrature Mirror Filter Banks

Iranian Journal of Electrical and Electronic Engineering, 2014
In this paper, a novel technique for the design of two-channel Quadrature Mirror Filter (QMF) banks with linear phase in frequency domain is presented. To satisfy the exact reconstruction condition of the filter bank, low-pass prototype filter response ...
S. K. Agrawal, O. P. Sahu
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Compact Muti-Frequency Band-Pass Filters Based on High-Order Mode of Folded Line Spoof Surface Plasmon Polaritons Waveguide

IEEE Access
We proposed a folded line spoof surface plasmonic polaritons (SSPPs) waveguide that allows for efficient and strongly constrained microwave SSPPs transmission.
Siyu Yang, Shuang Liu, Fachun He, Huali Zhu, Liangjing Wang, Dan Lei, Chan Gao, Jun Yan, kShuang Liu   +8 more
doaj   +1 more source

Fully-Differential Multifunctional Electronically Configurable Fractional-Order Filter with Electronically Adjustable Parameters

Elektronika ir Elektrotechnika, 2018
The paper presents a novel solution of a fully-differential 1+α fractional-order filter. The filter can provide low-pass, high-pass, band-pass and band-stop transfer functions without a necessity of a circuitry change (filter is electronically ...
Lukas Langhammer, Roman Sotner, Jan Dvorak, Tomas Dostal   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Compact band-pass electromechanical filter

Технологія та конструювання в електронній апаратурі, 2003
A comparison is presented between the characteristics of the proposed compact electromechanical filter in monolithic design and filters produced by Rockwell Collins.
Yu. E. Paerand
doaj  

Design, Analysis, and Fabrication of a Sharp Band-Pass Filter with Improved Pass-Band and Stop-Band Characteristics for 5G Mid-Band Applications

Magnetism
In this paper, a sharp band-pass filter (BPF) with enhanced pass-band and stop-band specifications is presented. The filter can be utilized for 5G mid-band applications along with LTE42 (3.4–3.6 GHz) and LTE43 (3.6–3.8 GHz) to comply with the standards ...
Abbas H. Ali, Falih M. Alnahwi, Yasir I. A. Al-Yasir   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

DESIGN OF BAND-PASS FILTERS WITH NON-EQUIRIPPLE FREQUENCY RESPONSES

Известия высших учебных заведений России: Радиоэлектроника, 2019
Introduction. Band-pass filters circuit elements can be calculated by converting low-pass filter (LPF) parameters, which is the prototype of the designed band-pass filter.
Evgeniy N. Chervinskiy
doaj   +1 more source