The Effectiveness, Safety and Cost-Effectiveness of Platelet-Rich Plasma and Platelet-Rich Fibrin in the Treatment of Venous Leg Ulcers: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Venous leg ulcers occur due to chronic venous insufficiency in the lower extremities and are often difficult to heal. Platelet‐rich plasma and platelet‐rich fibrin are products that contain high concentrations of platelets. This systematic review evaluated the effectiveness, safety and cost‐effectiveness of these products for the treatment of ...
Bui UT +6 more
europepmc +2 more sources
Reduced Clinical and Economic Burden Through Evidence-Based Dressing Selection for Wound Management: Findings From a Systematic Literature Review and Meta-Analysis. [PDF]
ABSTRACT The growing burden of wounds is placing pressure on clinicians and healthcare providers globally. This study aimed to determine the impact of using a hydrocellular polyurethane foam dressing (HPFD) on weekly dressing changes in mixed aetiology wounds.
Milne C +5 more
europepmc +2 more sources
Wound Care Knowledge of Community Pharmacists and Pharmacy Staff: A Cross-Sectional Survey. [PDF]
ABSTRACT Chronic wounds pose a public health challenge, with community pharmacists increasingly recognised for their potential role in wound care. Since all chronic wounds originate from acute wounds, pharmacists can play a proactive role in preventing chronicity.
Cheung DHK +3 more
europepmc +2 more sources
A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations. [PDF]
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Meslier T, D'Antin JC, Julio G, Roig A.
europepmc +2 more sources
Nanofibrous Platforms for Advanced Wound Therapeutics: Mechanisms, Materials, and Clinical Horizons
The fabrication of nanofiber dressings from diverse natural and synthetic polymers offers a robust platform for chronic wound management. By encapsulating therapeutic drugs and bioactive agents, these dressings can simultaneously attenuate chronic inflammation and microbial infection while actively stimulating angiogenesis, addressing the primary ...
Wanho Cho, Chungmo Yang, Hyuk Sang Yoo
wiley +1 more source
Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han +5 more
wiley +1 more source
Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt +7 more
wiley +1 more source
ABSTRACT Given the market for chronic wound care, where wound dressings are the key product, it should go without saying that providing satisfactory wound dressings is critical. A wide variety of wound dressings have been developed. Hydrogel has drawn attention as a potential wound dressing for chronic wounds. Hydrogel may absorb large amounts of water
Gianna Fadhilah +2 more
wiley +1 more source
ABSTRACT The ‘Wound Hygiene Italia’ project was designed to provide expert‐driven recommendations for the assessment, management and monitoring of venous leg ulcers, tailored to diverse settings of care (hospital, ambulatory and home care). The recommendations, developed by a multidisciplinary panel, emphasise the implementation of the Wound Hygiene ...
Alessandro Scalise +19 more
wiley +1 more source
Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco +4 more
wiley +1 more source

