ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh +8 more
wiley +1 more source
Factors Associated with Early Rebleeding After Endoscopic Variceal Ligation in Cirrhotic Patients: A Retrospective Cohort Study. [PDF]
Juncu S +15 more
europepmc +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Topical Peptide Technology and the Scarring Spectrum: Linking Mechanistic Pathways to Internal Scarring (Fibrous Banding) and External Scarring (Incisional) and Outcomes in Postsurgical Healing. [PDF]
Widgerow AD +4 more
europepmc +1 more source
<i>Chironomus</i> sp. J - an elusive species from the <i>Chironomus plumosus</i> (Linnaeus, 1758) sibling-species group (Diptera, Chironomidae). [PDF]
Golygina VV.
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Stay with me: rPL4 kidnaps the viral replicase to limit TVBMV infection. [PDF]
Uranga M.
europepmc +1 more source
Chromosome analysis by non-isotopic in situ hybridization. [PDF]
Cremer, Thomas +2 more
core +1 more source

