Results 231 to 240 of about 666,483 (294)

Targeted, receptor‐mediated delivery of a masked d‐amino acid cell‐penetrating peptide for cell‐specific phototoxicity

The FEBS Journal, EarlyView.
A targeted phototoxic peptide selectively accumulates in cells expressing chemokine‐like receptor 1 (CMKLR1). Phototoxicity of the native peptide is low, but cleavage by lysosomal protease cathepsin B releases a 6‐tetramethylrhodamine (TMR) labeled nona‐ᴅ‐arginine which mediates lysosomal rupture and cell death upon irradiation.
Moritz List, Eva‐Maria Jülke, Annette G. Beck‐Sickinger   +2 more
wiley   +1 more source

Constrictions and shear stress are key determinants of amyloidogenic light chain (AL) amyloidosis

The FEBS Journal, EarlyView.
In this study, we investigate how flow constrictions and shear stress trigger cardiac antibody light chain (AL) fibril formation and deposition. We mimic the mechanical forces exerted by the heart and the microvasculature network using a mini‐peristaltic pump setup and a grid‐type microchannel network, respectively.
Yuji Goto, Keiichi Yamaguchi, Kichitaro Nakajima, Ikuko Yumen, Ruiming He, Hirokazu Matsuda, Tetsuichi Wazawa, Takeharu Nagai, Nobuhiro Tsukada, Suguru Yamamoto, Johannes Buchner, Hirotsugu Ogi   +11 more
wiley   +1 more source

Mitochondrial iron homeostasis is required for azole tolerance in Candida albicans

The FEBS Journal, EarlyView.
In Candida albicans, the deletion of MRS4, which encodes a mitochondrial iron importer, abolishes fluconazole tolerance and increases cidality during cotreatment with the iron chelator BPS, without altering MIC or synergy. Fluconazole‐treated mutants exhibit increased mitochondrial depolarisation, fragmentation and reduced mitochondrial density.
Wouter Van Genechten, Gauthier Cornips, Martine De Jonge, Rudy Vergauwen, Patrick Van Dijck   +4 more
wiley   +1 more source

Clinical Outcomes After Catheter Ablation in Patients With Structural Heart Disease and Ventricular Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction In patients with ischemic cardiomyopathy (ICM), recurrent VF may be treated with catheter ablation by targeting triggering premature ventricular complexes (PVCs) and/or ventricular scar homogenization. Data on optimal ablation strategies in patients with non‐ischemic cardiomyopathy (NICM) remain limited.
Kenji Hashimoto, Samual Turnbull, Saurabh Kumar   +2 more
wiley   +1 more source

Spot the difference: Turbidity‐driven plasticity and variation in spotted grunter (Pomadasys commersonnii) spot patterns

Journal of Fish Biology, EarlyView.
Abstract Animal body markings such as spots, stripes and patterns play important roles in camouflage and visual communication. This study investigated phenotypic plasticity in the spot patterns of spotted grunter Pomadasys commersonnii, an estuarine‐dependent haemulid species.
Vivienne Coetzee, Denham Parker, Stephen Lamberth, Sven Kerwath   +3 more
wiley   +1 more source

Smart Coatings Integrating Antimicrobial and Tissue‐Remodeling Functions for Implant Interfaces

Journal of Periodontal Research, EarlyView.
Schematic illustration of a dental implant system showing inflammation around a non‐coated abutment (left) and a stimuli‐responsive coated abutment (right). Acidification associated with inflammation triggers degradation of the PMAA‐based coating, enabling controlled antibiotic release from the LbL system and combating bacterial infection.
Mariana Martins Guerreiro, Amanda Paino Santana, Daniela Moreira Cunha, Gabriel Mulinari‐Santos, Marlise Inêz Klein, Edilson Ervolino, Ludovica Parisi, Martin Degen, Maria Eduarda Fiorentino Ferreira de Andrade, Marta Maria Alves Pereira, Stefany Barbosa Alves da Cruz, Leonardo P. Faverani, Paula Aboud Barbugli, Rodolfo Debone Piazza, Vitória Marega Marchetti, Rodrigo Isaias Lopes Pereira, Rafael Scaf de Molon, Anton Sculean, Erica Dorigatti de Avila   +18 more
wiley   +1 more source

Development of sleepiness in professional truck drivers: Real‐road testing for driver drowsiness and attention warning (DDAW) system evaluation

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary All new vehicle types within the European Union must now be equipped with a driver drowsiness and attention warning system starting from 2022. The specific requirements for the test procedure necessary for type approval are defined in the Annex of EU Regulation C/2021/2639.
Christer Ahlström, Anna Anund
wiley   +1 more source

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Bandpass filters: theory and experiment

Applied Optics, 1983
On a montre que des mailles inductives avec des ouvertures de forme cruciforme peuvent etre de bons filtres passe-bande dans l'infrarouge ...
R C, Compton, R C, McPhedran
openaire   +2 more sources

Bandpass filtering in barium titanate

Applied Optics, 1988
Real-time spatial filteirng is performed in BaTiO(3) using two different holographic geometries. In both geometries white light images of moderate intensity are used to filter selected portions of Fourier transform holograms written in the crystal. The result is a suppression of certain spatial frequencies in the reconstructed images.
L, Pugliese, G M, Morris
openaire   +2 more sources

Bandpass filtering with lowpass filters

Journal of the Franklin Institute, 1963
Abstract Lowpass filters may achieve the effects of bandpass filtering by heterodyning the bandpass wave to obtain the “in-phase” and “quadrature” components and filtering these with suitable lowpass filters. The impulse responses for the lowpass filters are determined in a simple way from the desired bandpass impulse response.
openaire   +1 more source