Results 91 to 100 of about 249,023 (301)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

open access: yesAdvanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han   +6 more
wiley   +1 more source

Main determinants of efficiency and implications on banking concentration in the European Union

open access: yesRevista de Contabilidad: Spanish Accounting Review, 2019
This study aims to measure the main determinants influencing bank efficiency. We suggest that the bank efficiency ratio, obtained from the income statement, is positively related to the size of a bank in terms of total assets.
Rafael Bautista-Mesa, Horacio Molina
doaj   +1 more source

Income Diversification andFinancial Perfomance. Should Banks Trade

open access: yesjournal of accounting finance and auditing studies (JAFAS), 2019
Purpose:The purpose of this study is to examine the effect of income diversification on the financial performance of commercial banks in Kenya.Design/methodology/approach: The study used a sample of 31 commercial banks and panel data for the period 2008-2017.Data was extracted from the individual bank's financial reports and the Central Bank of Kenya's
Githaiga, Peter Nderitu   +2 more
openaire   +2 more sources

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

open access: yesAdvanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son   +2 more
wiley   +1 more source

The Evolving Financial System and Public Policy: Conference Highlights and Lessons [PDF]

open access: yes
At the 12th annual Bank of Canada economic conference, held in Ottawa on 4 and 5 December 2003, representatives from various public and private organizations and Bank of Canada staff discussed papers presented on three key issues affecting the financial ...
Carolyn Wilkins, Pierre St-Amant
core  

Essays on bank income diversification

open access: yes, 2018
This thesis investigates the effects of bank income diversification on bank performance and systemic stability in three independent but complementary empirical studies: The first study reviews the Glass–Steagall Act and similar specialized banking systems from a historic and macroeconomic perspective.
openaire   +3 more sources

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

open access: yesAdvanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv   +29 more
wiley   +1 more source

The risk effects of bank acquisitions [PDF]

open access: yes
An examination of the risk effects of bank acquisitions that occurred between the first quarter of 1984 and the last quarter of 1993. Its findings -- that banks are not using acquisitions to increase their risk exposure and that acquisitions increase ...
Ben Craig, João Cabral dos Santos
core  

Network versus portfolio structure in financial systems [PDF]

open access: yes, 2013
The question of how to stabilize financial systems has attracted considerable attention since the global financial crisis of 2007-2009. Recently, Beale et al.
Kobayashi, Teruyoshi
core   +3 more sources

Bank Diversification and Performance

open access: yesAdvances in Economics, Business and Management Research, 2021
Shujun Zhang   +5 more
openaire   +1 more source

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