It is time to increase Africa's governmental representation on the governing board of the global fund to fight AIDS, tuberculosis and malaria. [PDF]
Nalugala RM +6 more
europepmc +1 more source
Transforming Grain‐Boundary Brittle Precipitates to Ductility Pathways in Complex Concentrated Alloy
By engineering graded BCC/L12 interfaces, brittle precipitates in a complex concentrated alloy enable sequential deformation, realizing gigapascal strength with >20% elongation to solve the strength‐ductility trade‐off. ABSTRACT Conventional wisdom holds that hard grain‐boundary (GB) precipitates embrittle structural alloys by acting as crack ...
Zhixin Li +14 more
wiley +1 more source
Government subsidy research on the application of IoT technology in contract-farming supply chain. [PDF]
Zhou X, Peng Y, Xu B, Xiong WZ, Peng XM.
europepmc +1 more source
null Lastuti +2 more
openaire +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Multisectoral approaches to the prevention and control of vector-borne diseases: lessons learned from case studies. [PDF]
Nunes JB +8 more
europepmc +1 more source
Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang +11 more
wiley +1 more source
US divestment in global health: disruption, uncertainty and response. [PDF]
Franz C, Bozorgmehr K.
europepmc +1 more source
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou +6 more
wiley +1 more source
Advances in Research on the Biological Characteristics of Weedy Rice. [PDF]
Liang X +6 more
europepmc +1 more source

