Results 21 to 30 of about 6,003 (237)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
AGRICULTURAL CREDIT GUARANTEE SCHEME FUND AND ITS EFFECT ON AGRICULTURAL OUTPUT IN NIGERIA [PDF]
Research Background: Agricultural production in Nigeria experiences the challenge of inadequate funding particularly by farmers in rural areas. In an attempt to enhance farmers’ access to credit, the federal Government of Nigeria set up Agricultural ...
Jonathan REUBEN +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Sale of agricultural land in the Czech Republic after accession to the EU
This contribution concerns the current situation and development of sales of state agricultural land. There mentioned in detail are some conditions attached to subsidies provided by the programme "Land" (for purchase of land from private owners) and ...
J. Němec
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Jaminan E-Money pada Pariwisata Sariater Subang Menurut Tinjauan Hukum Ekonomi Syariah
The existence of DSN-MUI Fatwa Number 116/DSN-MUI/IX/2017 regarding electronic money, makes the ticket guarantee product from Sariater Ciater Subang Tourism, namely e-Money which has been released since its use until now has not received Sharia ...
Mas'ud Mas'ud, Rinaldy Agustian
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The BLBI dispute has been running for more than 20 years since the BLBI issued by the Government during the monetary crisis that occurred in Indonesia from 1997 to 1998, when the Government of Indonesia decided to implement a managed floating exchange rate system and free floating Until now, theproblem of Bank Indonesia Liquidity Assistance (BLBI) has ...
openaire +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source

