Results 81 to 90 of about 186,982 (313)
Financial Stability 2/06 [PDF]
, 2006 Financial stability means that the financial system is robust to disturbances to the economy and is able to channel funding, execute payments and redistribute risk in a satisfactory manner.
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Financial Stability 2/07 [PDF]
, 2007 Financial stability implies that the financial system is robust to disturbances in the economy and can channel capital, execute payments and redistribute risk in a satisfactory manner.
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Financial Stability 2/10 [PDF]
, 2010 Financial stability implies that the financial system is robust to disturbances and can channel capital, execute payments and redistribute risk in a satisfactory manner.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Bank prudential behaviour and bank stability – how far do they go
Journal of Banking and Financial Economics, 2017 This paper investigates how bank prudential behaviour affects bank stability, focusing only in the period after the global financial crisis. For this reason, we construct a new composite proxy as a measure for bank stability condition and another one for
Gerti Shijaku
doaj +1 more source
Bank reforms, competition, and stability in the Ghana banking industry
, 2020 Butkiewicz, James L.The central theme of my study is to assess the link between bank reforms, competition, and financial stability in the Ghana banking industry.
Antwi, James
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Financial Stability 1/11 [PDF]
, 2011 Financial stability implies that the financial system is robust to disturbances in the economy and can channel capital, execute payments and redistribute risk in a satisfactory manner. Financial stability is one of Norges Bank’s primary objectives in the
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