In Vivo Characterization of a Bank Vole-Derived Cowpox Virus Isolate in Natural Hosts and the Rat Model [PDF]
Viruses, 2020 Cowpox virus (CPXV) belongs to the genus Orthopoxvirus in the Poxviridae family and is endemic in western Eurasia. Based on seroprevalence studies in different voles from continental Europe and UK, voles are suspected to be the major reservoir host ...
Kathrin Jeske, Martin Beer, Jens Jacob
exaly +4 more sources
Molecular Detection and Characterization of the First Cowpox Virus Isolate Derived from a Bank Vole [PDF]
Viruses, 2019 Cowpox virus (CPXV) is a zoonotic orthopoxvirus (OPV) that infects a wide range of mammals. CPXV-specific DNA and antibodies were detected in different vole species, such as common voles (Microtus arvalis) and bank voles (Myodes glareolus).
Jens Jacob, Kathrin Jeske, Martin Beer
exaly +4 more sources
Geographical Distribution and Genetic Diversity of Bank Vole Hepaciviruses in Europe [PDF]
Viruses, 2021 The development of new diagnostic methods resulted in the discovery of novel hepaciviruses in wild populations of the bank vole (Myodes glareolus, syn. Clethrionomys glareolus). The naturally infected voles demonstrate signs of hepatitis similar to those
Bernd Hoffmann +2 more
exaly +4 more sources
Primary glia cells from bank vole propagate multiple rodent-adapted scrapie prions. [PDF]
Sci Rep, 2022 Since the beginning prion research has been largely dependent on animal models for deciphering the disease, drug development or prion detection and quantification. Thereby, ethical as well as cost and labour-saving aspects call for alternatives in vitro.
Schwenke KA +4 more
europepmc +2 more sources
Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring. [PDF]
Neurobiol DisPrion disease phenotypes (prion strains) are primarily determined by the specific misfolded conformation of the cellular prion protein (PrPC). However, post-translational modifications, including glycosyl phosphatidyl inositol (GPI) membrane anchoring ...
Vidal E +12 more
europepmc +2 more sources
Niche differentiation in a postglacial colonizer, the bank vole Clethrionomys glareolus. [PDF]
Ecol Evol, 2021 Species‐level environmental niche modeling has been crucial in efforts to understand how species respond to climate variation and change. However, species often exhibit local adaptation and intraspecific niche differences that may be important to ...
Escalante MA +3 more
europepmc +2 more sources
Effects of Climate and Land Use on the Population Dynamics of the Bank Vole (<i>Clethrionomys glareolus</i>) in the Southernmost Part of Its Range. [PDF]
Animals (Basel)This study investigated the effects of habitat structure and climatic variables on populations of bank voles (Clethrionomys glareolus), a northern species with adaptations to cooler climate, at the southern end of their range in Western Europe over a 16 ...
de la Huerta-Schliemann L +3 more
europepmc +2 more sources
Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion. [PDF]
PLoS Pathog, 2020 Prions are unorthodox pathogens that cause fatal neurodegenerative diseases in humans and other mammals. Prion propagation occurs through the self-templating of the pathogenic conformer PrPSc, onto the cell-expressed conformer, PrPC.
Burke CM +8 more
europepmc +2 more sources
The Bank Vole (Clethrionomys glareolus)-Small Animal Model for Hepacivirus Infection. [PDF]
Viruses, 2021 Many people worldwide suffer from hepatitis C virus (HCV) infection, which is frequently persistent. The lack of efficient vaccines against HCV and the unavailability of or limited compliance with existing antiviral therapies is problematic for health ...
Röhrs S +14 more
europepmc +2 more sources
A dynamic history of admixture from Mediterranean and Carpathian glacial refugia drives genomic diversity in the bank vole. [PDF]
Ecol Evol, 2021 Understanding the historical contributions of differing glacial refugia is key to evaluating the roles of microevolutionary forces, such as isolation, introgression, and selection in shaping genomic diversity in present‐day populations.
Horníková M +4 more
europepmc +2 more sources