Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
Drivers of international convergence in digital two-sided platform markets: The case of dominant business model components in online lending. [PDF]
Pur S, Huesig S, Schmidhammer C.
europepmc +1 more source
A large‐area, noise‐resilient multiplexed triboelectric sensing garment based on a multilayer shielded architecture and SnS2 nanoflower‐engineered hybrid materials enables interference‐suppressed, high‐fidelity full‐body motion tracking, achieving 0.13% signal misrecognition, 57 dB electromagnetic noise attenuation, and >1.5 N threshold force, while ...
Beibei Shao +14 more
wiley +1 more source
Commentary on Heirene and Newall: The architecture of risk assessment must be co-produced. [PDF]
Laidler F.
europepmc +1 more source
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu +10 more
wiley +1 more source
The Role of Sleep Banking in Reducing Cognitive and Motor Impairments from Subsequent Sleep Restriction: A Narrative Review. [PDF]
Juginović A, Rodman L.
europepmc +1 more source
The Role of Digital Maturity in Achieving the Quality of E-Services: An Analytical Study at Al-Rafidain Bank - Fallujah Branch. [PDF]
Akram Turki Y, Khawam Mahmood Z.
europepmc +1 more source
The adaptive engagement framework: enhancing banking customer experience through AI-powered invisible marketing. [PDF]
Shahbazi A +5 more
europepmc +1 more source
Anthropomorphic AI and Consumer Skepticism: A Behavioral Study of Trust and Adoption in Fragile Economies. [PDF]
Mackay ACD, Zuo L, Kebe IA.
europepmc +1 more source
Medical laboratory science course performance and grade point average as indicators of ASCP certification success: a 10-year review from an NAACLS-accredited program. [PDF]
Bushra S +5 more
europepmc +1 more source

