FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie+10 more
wiley +1 more source
D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing+9 more
wiley +1 more source
The effect of macroeconomic shocks on non-performing loans and credit risk in the iranian banking system using time-varying parameter vector autoregressions. [PDF]
Peykani P+4 more
europepmc +1 more source
Investigating the Determinants of Nonperforming Loans in the Romanian Banking System: An Empirical Study with Reference to the Greek Crisis [PDF]
Sofoklis Vogiazas, Eftychia Nikolaidou
openalex +1 more source
Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani+6 more
wiley +1 more source
Characteristics and dynamic evolution of inter-industry volatility spillovers in China's stock market. [PDF]
Xie F, Wei H.
europepmc +1 more source
The regulation framework for the banking sector: The EMU, European banks and rating agencies before and during the recent financial and debt crisis [PDF]
Konstantinos Liapis
openalex +1 more source
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu+16 more
wiley +1 more source
Divergent impacts of quantity versus price-based monetary policies on banking systemic risk: Evidence from China. [PDF]
Mo Y, Sun W, Ding Y, Wang L.
europepmc +1 more source