Results 221 to 230 of about 374,132 (362)

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

Advanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong, Jae‐Kook Cha, Wasim Ahmed, Jaewan Kim, Minsup Kim, Kyung Tae Hong, Wonji Choi, Sunjoo Choi, Tae Hyeon Yoo, Hyun‑Ju An, Seung Chan An, Jaemin Lee, Jimin Choi, Sun‐Young Kim, Jun‐Seok Lee, Soonchul Lee, Junwon Choi, Jin Man Kim   +17 more
wiley   +1 more source

Weathering the financial storm: The importance of fundamentals and flexibility [PDF]

The recent global financial tsunami has had economic consequences that have not been witnessed since the Great Depression. But while some countries suffered a particularly large contraction in economic activity on top of a system-wide banking and ...
Thorvardur Tjörvi Ólafsson, Thórarinn G. Pétursson   +1 more
core   +1 more source

Economic impacts and nutritional outcomes of the 2017 floods in Bangladeshi Shodagor fishing families

American Journal of Human Biology, Volume 35, Issue 1, January 2023., 2023
Abstract Objectives As climate change continues to increase the frequency and severity of flooding in Bangladesh and globally, it becomes increasingly critical to understand the pathways through which flooding influences health outcomes, particularly in lower‐income and subsistence‐based communities.
Kathrine E. Starkweather, Monica H. Keith, Fatema tuz Zohora, Nurul Alam   +3 more
wiley   +1 more source

Banking Crisis and Limited Creditor Protection [PDF]

, 2010
Eddy Wymeersch
openalex   +1 more source

The Market's View on the Probability of Banking Sector Failure: Cross-Country Comparisons [PDF]

Considering the increasingly international banks of today, the health of a country's banking sector is crucial not only to the country's growth and prosperity but also to the rest of the international financial community.
Hans Byström
core  

MISP Suppresses Ferroptosis via MST1/2 Kinases to Facilitate YAP Activation in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
This study explores the role of Mitotic Spindle Positioning (MISP) as a key inhibitor of ferroptosis in non‐small cell lung cancer (NSCLC). MISP upregulation in NSCLC tissues leads to ferroptosis resistance, promoting cell proliferation. Mechanistically, MISP suppresses Hippo signaling via MST1/2 kinases, activating YAP and enhancing SLC7A11 expression,
Fuquan Zhang, Bingtao Huang, Yiming Xu, Guohong Cao, Mingjing Shen, Changmin Liu, Judong Luo   +6 more
wiley   +1 more source

Analysis for health system resilience against the economic crisis: a best-fit framework synthesis. [PDF]

Health Res Policy Syst
Foroughi Z, Ebrahimi P, Yazdani S, Aryankhesal A, Heydari M, Maleki M.   +5 more
europepmc   +1 more source

How Useful are Regime-Switching Models in Banking Crises Identification? [PDF]

We employ a regime-switching approach to the identification of banking crises. This approach reduces the arbitrariness in crisis identification by endogenizing the choices of crisis threshold and crisis duration.
Tai-kuang Ho
core  

The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

Advanced Science, EarlyView.
This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan, Xuechao Wu, Jinxu Zhou, Weiqi Wu, Yuanliang Cao, Cuiping Sun, Zheng Li, Zhicheng Gong, Hong Tang, Qilin Li, Junsheng Chu, Qing Wang, Kaisa Cui, Xiaojie Lu   +13 more
wiley   +1 more source