Results 61 to 70 of about 40,210 (311)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

ONLINE BANKING IN THE ROMANIAN BANKING SYSTEM [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2014
In the world of banking, the development of IT has a huge effect on development of more flexible payments methods and more user-friendly banking services.
IMOLA DRIGĂ
doaj  

Systemic Risk in the Interbank Market with Overlapping Portfolios

open access: yesComplexity, 2019
The increasing frequency and scope of the financial crisis have attracted more attention in the research of the systemic risk of banking system. A new model for the interbank market with overlapping portfolios is proposed to simulate a banking system in ...
Shanshan Jiang, Hong Fan
doaj   +1 more source

Differences in Generation Y male and female customers’ perceived mobile banking trust, information, and system quality [PDF]

open access: yesBanks and Bank Systems
Trust is key to mobile banking adoption, shaping customer confidence in the service. Trusting behaviors and expectations vary between genders and across generational cohorts, influenced by factors like system and information quality. As such, the purpose
Marko van Deventer
doaj   +1 more source

Measuring the systemic importance of banks [PDF]

open access: yesJournal of Financial Stability, 2017
Abstract We provide a new metric for the systemic importance of banks based on the intensity of spillovers of daily CDS movements. We denote this a bank’s Individual Systemic Risk (ISR). Our novel empirical tool uses Bayesian VAR to address the dimensionality problem in large networks of banks and maps for every pair of banks in the system the shocks
Georgios Moratis, Plutarchos Sakellaris
openaire   +3 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Banking system stability and economic sustainability: A panel data analysis of the effect of banking system stability on sustainability of some selected developing countries

open access: yesQuantitative Finance and Economics, 2019
The study investigated the effects of banking system stability on economic sustainability from the perspective of 37 developing economies for the period 2000–2016.
Albert Henry Ntarmah   +2 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

POTENSI DAN STRATEGI PENGEMBANGAN BANK SYARI’AH DI INDONESIA: KAJIAN PRODUK SYARI’AH DARI SEGI FIQIH MU’AMALAT

open access: yesJurnal Hukum Islam, 2011
At the present, Indonesia operate dual banking system that are conventional banking system with its interest rate runs side by side and the Islamic banking with the profit-sharing/non-interest system of its own.
Anny Ratnawati
doaj   +1 more source

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