Results 181 to 190 of about 5,628 (258)

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology

open access: yesAnnals of Neurology, EarlyView.
Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko   +8 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

open access: yesAngewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej   +20 more
wiley   +2 more sources

Optimizing family building in women of advanced reproductive age: a Faster-Fewer-and-Finished approach. [PDF]

open access: yesFront Endocrinol (Lausanne)
Sunkara SK   +6 more
europepmc   +1 more source

Deciphering the Role of Energy Transfer Configuration in PFAS Recognition by Metal‐Organic Frameworks

open access: yesAngewandte Chemie, EarlyView.
Spatial organization of Eu/Tb centers in EuTb‐FDA MOFs is employed to regulate Tb‐to‐Eu energy transfer configuration for ratiometric PFAS sensing. Directional energy transfer amplifies PFAS‐induced optical perturbations into opposite lanthanide emission responses, with enhanced Tb emission and quenched Eu emission, thereby amplifying the sensing ...
Jiatong Huo   +5 more
wiley   +2 more sources

A quantum reservoir computing approach to quantum stock price forecasting in technology-markets. [PDF]

open access: yesEPJ Quantum Technol
Otieno W   +4 more
europepmc   +1 more source

Newborn screening and biobanking for preventable genetic disorders in Mongolia: A developing country perspective. [PDF]

open access: yesRegen Ther
Batchuluun K   +10 more
europepmc   +1 more source

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