Results 221 to 230 of about 399,821 (301)

Ensuring the sovereignty and security of Canadian health data. [PDF]

CMAJ
Geist M, Teitelbaum M, Wilson K.
europepmc   +1 more source

Enhanced Sensitivity of a Modified Quaking‐Induced Conversion Diagnostic Test for the Broad Detection of Sporadic and Inherited Prion Diseases: A Retrospective Study

Annals of Neurology, EarlyView.
Objective Quaking‐induced conversion (QuIC) tests, which detect prion‐seeding activity in cerebrospinal fluid (CSF), have markedly advanced the antemortem diagnosis of prion diseases such as Creutzfeldt‐Jakob disease (CJD). These tests provide high diagnostic accuracy and enable timely differentiation from other rapidly progressive neurodegenerative ...
Jennifer Myskiw, Rebecca Fox, Dominic M.S. Kielich, Lise Lamoureux, Melanie Leonhardt, Olivia Nykvist, Jessy A. Slota, Kristen Avery, Clark Phillipson, Kathy Frost, Sharon Simon, Brian S. Appleby, Ben A. Bailey‐Elkin, Stephanie A. Booth   +13 more
wiley   +1 more source

AI-Driven Innovations in Transfusion Medicine: A Narrative Synthesis of Current Reviews. [PDF]

Med Sci (Basel)
Giansanti D, Cosenza C.
europepmc   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

Changes in the pH value of the human brain in Alzheimer's disease pathology correlated with CD68-positive microglia: a community-based autopsy study in Beijing, China. [PDF]

Mol Brain
Wang X, Shao X, Yu L, Sun J, Yin XS, Chen Z, Xu Y, Wang N, Zhang D, Qiu W, Liu F, Ma C.   +11 more
europepmc   +1 more source

Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort

Annals of Neurology, EarlyView.
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov, Ivana Dzinovic, Theresa Brunet, Vicente A. Yépez, Florian Hölzlwimmer, Elisabetta Indelicato, Birgit Assmann, Susann Badmann, Diana Ballhausen, Steffen Berweck, Felix Brechtmann, Melanie Brugger, Kevork Derderian, Felix Distelmaier, Philip Harrer, Denisa Harvanova, Petra Havrankova, Ann‐Kathrin Jaroszynski, Miriam Kolnikova, Robert Kopajtich, Anne Koy, Magdalena Krygier, Lukas Kunc, Katarina Kusikova, Oliver Maier, Maria Mazurkiewicz‐Bełdzińska, Christian Mertes, Ava Oberlack, Timo Roser, Alexandra Sitzberger, Ugo Sorrentino, Antonia M. Stehr, Katharina Vill, Matias Wagner, Holger Prokisch, Sylvia Boesch, Jan Necpal, Robert Jech, Juliane Winkelmann, Elisabeth Graf, Julien Gagneur, Matej Skorvanek, Michael Zech   +42 more
wiley   +1 more source

Aging well in an aging society: Italy at the forefront of global aging and the Age-It Research Program. [PDF]

J Gerontol B Psychol Sci Soc Sci
Vignoli D, Albertini M, Chiatti C, Aimaretti G, Boccuzzo G, Boffo V, Brugiavini A, Cavallo F, Cenci S, Cherubini A, Cincotti F, d'Adda di Fagagna F, Ferrarese C, Galasso V, Galeotti E, Graziani A, Iaccarino G, Lattanzio F, Lucifora C, Mezzanzanica M, Passarino G, Paterno A, Prati S, Rumiati RI, Sandri M, Tomassini C, Torbica A, Ungar A, Petrucci A.   +28 more
europepmc   +1 more source

A Growth Chart for KBG Syndrome

American Journal of Medical Genetics Part A, EarlyView.
Karen J. Low, Elena Martinez‐Cayuelas, Berta Almoguera, Purin Marin‐Reina, Allan Bayat, Charlotte W. Ockeloen, Tim J. Cole   +6 more
wiley   +1 more source

Baseline Characteristics of Pristine Agricultural Pods Biochar

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The valorization of agricultural pod wastes into biochar offers a sustainable pathway for waste management and the development of functional carbonaceous materials. This study comparatively evaluates biochars produced from cocoa, flamboyant, and locust bean pods using an autothermal top‐lit updraft gasifier with retort heating, a system ...
Bolaji Ibrahim Busari, Ghadah M. Al‐Senani, Stephen Sunday Emmanuel, Salhah D. Al‐Qahtani, Ebuka Chizitere Emenike, Kingsley O. Iwuozor, Abel U. Egbemhenghe, Rafiu Olasunkanmi Yusuf, Adewale George Adeniyi   +8 more
wiley   +1 more source

Interpretation guidance for MHRA regulatory considerations for phage therapeutic products. [PDF]

Microbiology (Reading)
Coxon C, Bell E, Adriaenssens E, Clark J, Edwards J, Gohir T, Hodges F, Jones J, Rees C, Sansom A, Smith D, Sutton M, Trippett C, Turner D.   +13 more
europepmc   +1 more source