Results 61 to 70 of about 555,393 (323)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Liability of construction participants for delays

Business, Management and Education, 2011
Date of completion is usually set forth in construction contract agreements as one of the most important provisions. Also, it is the provision, which is often violated and the violation results in a dispute between the parties to the agreement.
Sigitas Mitkus, Aurelija Sekonaitė
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Interpreting Bar Charts: Effects of 3D Depth Cues on Human Gaze and User Understanding

Digital
Three-dimensional information visualizations are widely used in various fields for their aesthetic appeal. However, using them can sometimes lead to occlusion and distortion, which raises questions about when and why to use them.
Ana Svalina, Dubravko Banić, Dorotea Kovačević   +2 more
doaj   +1 more source

3D printing for bio-synthetic biliary stents [PDF]

, 2019
Three-dimensional (3D) printing is an additive manufacturing method that holds great potential in a variety of future patient-specific medical technologies.
Alexander, Jonathan Steven, Ballard, David, Boktor, Moheb, Boktor, Moheb, Boyer, Christen J., Ghali, G.E., Huebert, Robert, Samant, Hrishikesh, Wang, Yuping, White, Luke, Woerner, Jennifer E.   +10 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A New X-bar Control Chart for Multiple Dependent State Sampling Using Neutrosophic Exponentially Weighted Moving Average Statistics with Application to Monitoring Road Accidents and Road Injuries [PDF]

, 2021
Nasrullah Khan, Liaquat Ahmad, G. Srinivasa Rao, Muhammad Aslam, Ali Hussein AL-Marshadi   +4 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Design of X-bar control chart based on Inverse Rayleigh Distribution under repetitive group sampling

Ain Shams Engineering Journal, 2021
The X¯ control chart is usually used in statistical quality control (SQC) to observe the change in procedure mean. In this paper, X¯ control chart for Inverse Rayleigh Distribution (IRD) is designed under repetitive group sampling at lower record values.
Ambreen Shafqat, Zhensheng Huang, Muhammad Aslam   +2 more
doaj   +1 more source

Economic design of X-bar control chart using simulated annealing [PDF]

, 2011
Control charts are widely used in industry for monitoring and controlling manufacturing processes. They should be designed economically in order to achieve minimum quality control costs.
Darun , Prasath.L
core