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Quality of life up to 10 years after traumatic brain injury: a cross-sectional analysis

Health and Quality of Life Outcomes, 2020
Background Traumatic brain injury (TBI) is the leading cause of death and disability among children and young adults in industrialized countries, but strikingly little is known how patients cope with the long-term consequences of TBI.
Katrin Rauen +6 more
doaj +1 more source

A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity

Clinical and Translational Medicine, 2021
Background and aims Mutations in KCNH2 cause long or short QT syndromes (LQTS or SQTS) predisposing to life‐threatening arrhythmias. Over 1000 hERG variants have been described by clinicians, but most remain to be characterised.
Barbara Oliveira‐Mendes +16 more
doaj +1 more source

Falta de dentição funcional influencia na autopercepção da necessidade de tratamento em adultos: estudo de base populacional no Brasil

Cadernos de Saúde Coletiva, 2018
Resumo Introdução A falta de dentição funcional compromete a qualidade de vida dos indivíduos, podendo refletir nas suas percepções, incluindo a autopercepção da necessidade de tratamento odontológico.
Carolina Veloso Lima +5 more
doaj +1 more source

Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia

JACC: Asia, 2021
Background: The coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known.
Takashi Kudo, MD, PhD +1205 more
doaj +1 more source

Ostranenie Does Not Equal Ozvláštnění: An Issue of a Term Transferred and Misunderstood // [PDF]

Slovo a Smysl, 2015
The text focuses on the question of the transfer and translation of several Formalist concepts, such as ostranenie and tochka zrenia. The interpretation is based on Boris Uspensky’s A Poetics of Composition, it revisits the original definition provided
Libuše Heczková, Kateřina Svatoňová
doaj

Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau

Alzheimer’s Research & Therapy, 2019
Background Augmenting the brain clearance of toxic oligomers with small molecule modulators constitutes a promising therapeutic concept against tau deposition.
Matthias Brendel +20 more
doaj +1 more source

Varied motivations for secondary forest reclearing among landholders make forest persistence challenging

People and Nature, Volume 8, Issue 6, Page 1943-1956, June 2026.
Abstract Remote sensing studies show that ephemeral forest regeneration is widespread in the tropics, limiting the climate and biodiversity benefits from net increases in forest cover. Socioeconomic, biophysical and landscape variables can help explain the spatial distribution of reforestation reversals.
Francis H. Joyce
wiley +1 more source

Comparing land use regression and dispersion modelling to assess residential exposure to ambient air pollution for epidemiological studies

Environment International, 2014
Background: Land-use regression (LUR) and dispersion models (DM) are commonly used for estimating individual air pollution exposure in population studies. Few comparisons have however been made of the performance of these methods.
Kees de Hoogh +41 more
doaj +1 more source

Potential Impacts of Climate Interventions on Marine Ecosystems

Reviews of Geophysics, Volume 64, Issue 1, March 2026.
Abstract Rising global temperatures pose significant risks to marine ecosystems, biodiversity, and fisheries. Recent comprehensive assessments suggest that large‐scale mitigation efforts to limit warming are falling short, and all feasible future climate projections, including those that represent optimistic emissions reductions, exceed the Paris ...
Kelsey E. Roberts +25 more
wiley +1 more source

Genome-wide association and functional follow-up reveals new loci for kidney function.

PLoS Genetics, 2012
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and stratified for key CKD risk factors. We uncovered 6 new
Cristian Pattaro +169 more
doaj +1 more source

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