Results 211 to 220 of about 989,828 (305)

Impact of Evolving Treatment Patterns on Interstitial Lung Disease Progression in Systemic Sclerosis Using the European Scleroderma Trials and Research Database

open access: yesArthritis &Rheumatology, EarlyView.
Objective The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasingly available immunosuppressive therapies (ISTs) and antifibrotic treatments. However, their real‐world use remains unclear.
Corrado Campochiaro   +17 more
wiley   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

open access: yesArthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller   +16 more
wiley   +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

Repositioned Kirschner Wires as a Temporary Metaphyseal Block to Prevent Articular Extension During Opening‐Wedge High Tibial Osteotomy

open access: yesArthroscopy Techniques, EarlyView.
Abstract Lateral hinge fracture is a frequent complication of medial opening‐wedge high tibial osteotomy. Previous strategies—such as inserting an additional third Kirschner wire (K‐wire) from the lateral tibial cortex—reinforce the lateral cortex but do not address the potential fracture line that propagates proximally toward the tibial plateau and ...
Luis García Bordes   +6 more
wiley   +1 more source

Correction: Understanding Biologics in CRSwNP: Related Events and Insights. [PDF]

open access: yesCurr Allergy Asthma Rep
Izquierdo-Domínguez A   +4 more
europepmc   +1 more source

Mini‐Open Short Superficial and Deep Medial Collateral Ligament Reconstruction of the Knee With Adjustable System

open access: yesArthroscopy Techniques, EarlyView.
Abstract Successful medial collateral ligament (MCL) reconstruction depends on multiple anatomical and biomechanical factors. Various techniques have been described, ranging from isolated superficial MCL reconstructions to complex combined medial reconstructions.
Pablo Gelber   +2 more
wiley   +1 more source

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