Results 21 to 30 of about 322,175 (261)

Long-term drought variability and trends in Barcelona (1787-2014)

open access: yesCuadernos de Investigación Geográfica, 2016
Long-term drought variability and trends were assessed in Barcelona at annual and seasonal scale for the period 1787-2014 and sub-periods 1851-2014, 1901-2014 and 1951-2014 to identify changes in drought patterns across time.
J. R. Coll   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Rodrigo y Alharilla, Martín y Chaviano Pérez, Lizbeth (2017): Negreros y esclavos. Barcelona y la esclavitud atlántica (siglos XVI-XIX). Barcelona: Icaria

open access: yesmethaodos.revista de ciencias sociales, 2021
El propósito del libro es poner de relieve los intensos vínculos y la insersión en las dinámicas del capitalismo esclavista, en la importancia económica de la ciudad de Barcelona (y, Cataluña en general) en la esclavitud atlántica.
Joan Lara Amat y León
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

«Vergüenza y ludibrio de las ciudades modernas»: los nacionalistas catalanes ante el flamenco en la Barcelona de 1900-1936

open access: yesHispania, 2013
Este artículo analiza el flamenco, el anti-flamenquismo y las identidades nacionales en Barcelona durante las tres décadas anteriores a la Guerra Civil. Así, estudia los significados de los espacios musicales impugnados por los nacionalistas catalanes. A
Sandie Holguín
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

L 'abastament de blat a la ciutat de Barcelona en temps d'Alfons el Benigne (1327-1336)

open access: yesAnuario de Estudios Medievales, 2001
L'objecte d'aquest article es estudiar la qüestió de la penúria de cereals a Barcelona durant el regnat d'Alfons el Benigne. Es tracten diferents aspectes com ho son: les causes de l'endèmica escassetat de blat a Barcelona, la política cerealística ...
Josefina Mutgé i Vives
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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