Results 41 to 50 of about 391,996 (300)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
RA. Revista de Arquitectura, 2015 El artículo expone, apoyándose en una extensa documentación gráfica original e inédita, la trayectoria y arquitectura del pabellón de Suecia diseñado por Peder Clason para la Exposición Internacional de Barcelona de 1929.
Gerardo García-Ventosa i López
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Environment and Planning, 2019 Short-term rentals facilitated by online platforms (like Airbnb) have recently become a subject of intense debate, leading many city governments to pass new regulations attempting to control both their proliferation and platform activities.
Thomas Aguilera +2 more
semanticscholar +1 more source
Defining a historic football team: Using Network Science to analyze Guardiola’s F.C. Barcelona [PDF]
Scientific Reports, 2019 The application of Network Science to social systems has introduced new methodologies to analyze classical problems such as the emergence of epidemics, the arousal of cooperation between individuals or the propagation of information along social networks.
J. M. Buldú +6 more
semanticscholar +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Long-term drought variability and trends in Barcelona (1787-2014)
Cuadernos de Investigación Geográfica, 2016 Long-term drought variability and trends were assessed in Barcelona at annual and seasonal scale for the period 1787-2014 and sub-periods 1851-2014, 1901-2014 and 1951-2014 to identify changes in drought patterns across time.
J. R. Coll +3 more
doaj +1 more source
Spatial hazard assessment of the PM10 using machine learning models in Barcelona, Spain.
Science of the Total Environment, 2019 Air pollution, and especially atmospheric particulate matter (PM), has a profound impact on human mortality and morbidity, environment, and ecological system. Accordingly, it is very relevant predicting air quality.
Bahram Choubin +6 more
semanticscholar +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Environmental Science and Policy, 2019 Highlights • Three regulating ecosystem services (ES) provided by street trees are quantified.• Associations between street tree ES and five socioeconomic variables are analyzed.• Street tree ES are positively associated to the distribution of vulnerable
F. Baró +3 more
semanticscholar +1 more source