Results 161 to 170 of about 59,630 (306)
Three-Dimensional CT Planning for Anatomic Shoulder Arthroplasty: Reliability of Version Correction With Short-Term Clinical Outcomes. [PDF]
Thakkar AP +7 more
europepmc +1 more source
Da’ish, Stasis and Bare Life in Iraq [PDF]
Simon Mabon, Ana Maria Kumarasamy
openalex +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Robust and durable zwitterionic hydrogel coating with catechol-Cu<sup>2+</sup> coordination for antithrombotic and antibacterial blood-contacting devices. [PDF]
Bai G, Xie Y, Sun Y, Li L, Zhu Y, Li X.
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Factors influencing early post-wildfire vegetation and implications for invasive plant management in the interior of British Columbia, Canada. [PDF]
Oeggerli VV +3 more
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

