Results 101 to 110 of about 141,713 (348)

Mechanisms Underlying Weight Loss and Metabolic Improvements in Rodent Models of Bariatric Surgery [PDF]

, 2014
Obesity is a growing health risk with few successful treatment options and fewer still that target both obesity and obesity-associated comorbidities. Despite ongoing scientific efforts, the most effective treatment option to date was not developed from ...
Arble, Deanna M., Sandoval, Darleen A., Seeley, Randy J.   +2 more
core   +2 more sources

Patterns of parenteral nutrition use in the inpatient setting: A retrospective cohort study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Parenteral nutrition (PN) supports patients unable to absorb sufficient nutrients from their gastrointestinal tracts. Yet, information about the patterns and extent of PN's in‐hospital use is lacking. Data on this topic should provide comparison points for nutrition support teams and hospital administrators examining PN use in their
Marc Romain, Charles Weissman, Khuloud Abu‐Tair, Abdallah Alla Aldin, Rivki Harari, Orit Bitner, Alexander Furmanov, Shaul Yaari   +7 more
wiley   +1 more source

Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP‐1 Receptor Agonists: A Network Meta‐Analysis of Randomized Controlled Trials

Obesity, EarlyView.
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella, Patricia M. Ortega, Víctor Valentí Azcárate, Fernando Rotellar Sastre, Adriana Uriz Pagola, Ahmed Ahmed, Sanjay Purkayastha, Carlota Tuero Ojanguren, Nuria Blanco Asensio, Manuel F. Landecho   +9 more
wiley   +1 more source

The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial [PDF]

, 2016
Background: Despite improving evidence-based practice following clinical guidelines to optimise drug therapy, Type 2 diabetes (T2DM) still exerts a devastating toll from vascular complications and premature death.
Adamson, Ashley, Barnes, Alison, Brosnahan, Naomi, Ford, Ian, Hollingsworth, Kieren G., Kean, Sharon, Lean, Mike E.J., Leslie, Wilma S., Mathers, John C., McCombie, Louise, McIlvenna, Yvonne, Peters, Carl, Rehackova, Lucia, Rodrigues, Angela, Ross, Hazel, Sattar, Naveed, Sniehotta, Falko F., Taylor, Roy, Thom, George, Zhyzhneuskaya, Sviatlana   +19 more
core   +3 more sources

Addition of Phentermine‐Topiramate to a Digitally Enhanced Lifestyle Intervention: A Double‐Blind Randomized Clinical Trial

Obesity, EarlyView.
ABSTRACT Objective This study compared the effects of phentermine‐topiramate‐ER (mid‐dose 7.5/46 mg) versus placebo on weight loss and cardiovascular disease (CVD) risk outcomes when used as an adjunct to a digitally enhanced lifestyle intervention (DELI).
Alejandro Campos, Wissam Ghusn, Lizeth Cifuentes, Daniel Sacoto, Sima Fansa, Diego Anazco, Maria L. Ricardo‐Silgado, Anas Hashem, Megan Schaefer, William S. Harmsen, Heather J. Gunn, Craig Peterson, Deborah Larsen, Santosh T. Varghese, Maria D. Hurtado, Andres Acosta   +15 more
wiley   +1 more source

Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

, 2022
Julie Steen Pedersen, Marte Opseth Rygg, Karoline Maise Chrøis, Elahu G. Sustarsic, Zachary Gerhart‐Hines, Nicolai J. Wewer Albrechtsen, Reza Serizawa, Viggo B. Kristiansen, A. Basse, Astrid E. B. Boilesen, Beth Hærstedt Olsen, Torben Hansen, Lise Lotte Gluud, Sten Madsbad, Steen Larsen, Flemming Bendtsen, Flemming Dela   +16 more
openalex   +1 more source

Impact of Bariatric Surgery on the Stability of the Genetic Material, Oxidation, and Repair of DNA and Telomere Lengths [PDF]

, 2023
Franziska Ferk, Miroslav Mišík, Benjamin Philipp Ernst, Gerhard Prager, Christoph Bichler, Doris Mejri, Christopher Gerner, Andrea Bileck, Michael Kundi, Sabine A. S. Langie, Klaus Holzmann, Siegfried Knasmueller   +11 more
openalex   +1 more source

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

Obesity, EarlyView.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden, Maria A. Oquendo, Robert F. Kushner, Dachuang Cao, Chrisanthi A. Karanikas, Afton Kechter, Madhumita A. Murphy   +6 more
wiley   +1 more source

Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery [PDF]

, 2018
Vance L. Albaugh, Babak Banan, Joseph Antoun, Yanhua Xiong, Yan Guo, Jie Ping, Muhammed Alikhan, Blake Austin Clements, Naji N. Abumrad, Charles R. Flynn   +9 more
openalex   +1 more source

Impact of weight loss on brain age: Improved brain health following bariatric surgery

, 2022
Yashar Zeighami, Mahsa Dadar, Justine Daoust, Mélissa Pelletier, Laurent Biertho, Léonie Bouvet-Bouchard, Stephanie Fulton, André Tchernof, Alain Dagher, Denis Richard, Alan C. Evans, Andréanne Michaud   +11 more
openalex   +1 more source