Results 101 to 110 of about 52,166 (258)

Time‐Restricted Eating on Appetite and Inflammation in Adults With Obesity and Prediabetes: A Randomized Feeding Study

Obesity, EarlyView.
ABSTRACT Objective Time‐restricted eating (TRE) has gained attention for weight loss and cardiometabolic health improvement. The Time‐Restricted Intake of Meals (TRIM) study was a 12‐week randomized isocaloric and eucaloric feeding trial comparing 10‐h TRE to a 16‐h usual eating pattern (UEP) in adults with obesity and either prediabetes or diet ...
Daisy Duan, Susan Carnell, Scott J. Pilla, Stephanie T. Chung, Jeanne M. Clark, Nisa M. Maruthur   +5 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Obstructive Sleep Apnea and BMI, Body Fat Percentage in the East Asian Population: A Bidirectional and Multivariate Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan, Wen‐Jun Lu, Hua Zhang, Hai‐Ling Jiang, Tao Li, Yan Yan   +5 more
wiley   +1 more source

The gut microbiome enhances breast cancer immunotherapy following bariatric surgery

JCI Insight
Bariatric surgery is associated with improved breast cancer (BC) outcomes, including greater immunotherapy effectiveness in a preclinical BC model. A potential mechanism of bariatric surgery–associated protection is the gut microbiota.
Margaret S. Bohm, Sydney C. Joseph, Laura M. Sipe, Minjeong Kim, Cameron T. Leathem, Tahliyah S. Mims, Nathaniel B. Willis, Ubaid A. Tanveer, Joel H. Elasy, Emily W. Grey, Madeline E. Pye, Zeid T. Mustafa, Barbara Anne Harper, Logan G. McGrath, Deidre Daria, Brenda Landvoigt Schmitt, Jelissa A. Myers, Patricia Pantoja Newman, Brandt D. Pence, Marie Van der Merwe, Matthew J. Davis, Joseph F. Pierre, Liza Makowski   +22 more
doaj   +1 more source

Post-bariatric pregnancy is associated with vitamin K1 deficiency, a case control study

BMC Pregnancy and Childbirth
Background Maternal obesity is associated with adverse outcome for pregnancy and childbirths. While bariatric surgery may improve fertility and reduce the risk of certain pregnancy-related complications such as hypertension and gestational diabetes ...
Brit Torunn Bechensteen, Cindhya Sithiravel, Ellen Marie Strøm-Roum, Heidi Kathrine Ruud, Gunnhild Kravdal, Jacob A. Winther, Tone G. Valderhaug   +6 more
doaj   +1 more source

Becoming monstrous: Beauty norms, body image, and discursive limits on compassion in The Substance

Nutrition &Dietetics, EarlyView.
Abstract Aim This study analyses the Hollywood body horror film The Substance to explore how Western beauty culture regulates emotions and bodies. It aims to explore compassion within dominant body image discourses and considers how this impacts dietetic care. Methods Using Foucauldian discourse analysis informed by affect theory, the film was analysed
Phillip Joy
wiley   +1 more source

Impact of bariatric surgery on alcohol‐use disorder and alcohol‐related liver disease: A retrospective study

Addiction, EarlyView.
Abstract Background and aims Increased risk of alcohol dependence is recognised following bariatric surgery. Modified gastrointestinal anatomy and neurohormonal profiles lead to altered alcohol metabolism, peak blood alcohol concentrations and enhanced reward circuits and cravings.
Thomas J. Williams, Andrew J. Palmer, Jason P. Connor, Gerald Holtmann, Paul J. Clark   +4 more
wiley   +1 more source

Prognostic significance of prior alcohol use disorder in patients with presumed metabolic dysfunction‐associated steatotic liver disease: A large multi‐center cohort study

Addiction, EarlyView.
Abstract Background and aims Alcohol use disorder (AUD) follows a chronic, relapsing course but is often overlooked when alcohol consumption is minimal at the time of evaluation. We aimed to assess the prognostic impact of a prior AUD diagnosis on liver‐related outcomes in patients with presumed metabolic dysfunction‐associated steatotic liver disease (
Butros Fakhoury, Jinye Liu, Vinay Jahagirdar, Kaanthi Rama, Gerald Scott Winder, Luis Antonio Díaz, Juan Pablo Arab   +6 more
wiley   +1 more source

Insomnia and depression among bariatric surgery patients: the chain mediating effect of resilience and anxiety

Frontiers in Psychiatry
ObjectiveThis study aimed to examine the psychological mechanisms of depression in both bariatric surgery candidates and post-bariatric surgery patients and to explore the roles of resilience and anxiety in these relationships.MethodsA total of 431 ...
Jijian Si, Yixin Zhang, Manyuan Li, Tour Liu, Tour Liu, Tour Liu   +5 more
doaj   +1 more source