Results 281 to 290 of about 141,713 (348)

Efficacy and Safety of Pharmacological, Endoscopic, and Surgical Treatments for Obesity: A GRADE‐Based Network Meta‐Analysis

open access: yesObesity, Volume 34, Issue 2, Page 279-293, February 2026.
ABSTRACT Objective This review compared antiobesity strategies—obesity management medications (OMM), endoscopic bariatric procedures (EBP), and metabolic bariatric surgery (MBS)—with lifestyle intervention, placebo, or no therapy (LSI/Pbo/NT). Methods This network meta‐analysis included randomized clinical trials comparing OMM, EBP, and MBS versus LSI ...
Maurizio De Luca   +12 more
wiley   +1 more source

Glucose-Dependent Insulinotropic Polypeptide and Glucagon After Weight Loss Induced by Diet or Bariatric Surgery

open access: gold
Anja Finn   +4 more
openalex   +1 more source

Targeted Next‐Generation Sequencing of the Leptin‐Melanocortin Pathway in Severe Obesity

open access: yesObesity, Volume 34, Issue 2, Page 499-511, February 2026.
ABSTRACT Objective Pathogenic variants in five established leptin‐melanocortin pathway genes (LEP, LEPR, MC4R, PCSK1, POMC) are associated with severe early‐onset obesity and are targets for emerging treatments. However, these variants are rare in these patients, suggesting the involvement of additional genes interacting with this pathway. Methods Next‐
Nathan Faccioli   +12 more
wiley   +1 more source

Metabolic Outcomes in Patients With Type 2 Diabetes Prescribed Incretin‐Based Therapy and Referred or Not to a Weight Management Clinic: A Single‐Center Retrospective Analyses

open access: yesObesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Background Incretin therapies yield strong metabolic improvements, but whether adding a weight‐management (WM) clinic confers additional benefit beyond pharmacotherapy alone in routine care is unclear. Objective Evaluate whether referral to WM clinic, alongside standard diabetes care, provides additional benefit for adults with type 2 diabetes
Kathleen M. Robinson   +5 more
wiley   +1 more source

Variation of metabolic and bariatric surgery utilization by neighborhood socioeconomic status in Maryland. [PDF]

open access: yesPLoS One
Akinyemi O   +7 more
europepmc   +1 more source

Lifespan‐Extending Endogenous Metabolites

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Early Impact of Bariatric Surgery on Brain Functionality. [PDF]

open access: yesJ Metab Bariatr Surg
Fernandes BB   +9 more
europepmc   +1 more source

A Review of the Management of Obesity in Primary Care

open access: yesClinical Obesity, Volume 16, Issue 1, February 2026.
ABSTRACT This review highlights the important role primary care plays in obesity management, using England as an example. It includes a comprehensive summary of current management and referral options for primary care clinicians, a discussion of the most up‐to‐date clinical guidelines for the use of GLP‐1 receptor agonists in England, and the evolving ...
H. M. Parretti   +7 more
wiley   +1 more source

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