Treatment patterns, persistence with therapy, and outcomes of ustekinumab in Crohn's disease: Real‐world data analysis [PDF]
Background and Aim In 2017, ustekinumab (UST) was included in Israel's National Basket of Health Services for treatment of biologic‐experienced Crohn's disease (CD) patients with moderately to severely active disease.
Tamar Banon +5 more
doaj +3 more sources
Pruritogens in pemphigoid diseases: Possible therapeutic targets for a burdensome symptom. [PDF]
Abstract Pruritus is a hallmark feature in pemphigoid diseases, where it can be severe and greatly impact the quality of life of affected patients. Despite being a key symptom, the exact pathophysiological mechanisms involved in pruritus in pemphigoid are yet to be fully elucidated and effective therapies addressing them are limited.
Hiroyasu S +3 more
europepmc +2 more sources
Soft robotics towards sustainable development goals and climate actions [PDF]
Soft robotics technology can aid in achieving United Nations’ Sustainable Development Goals (SDGs) and the Paris Climate Agreement through development of autonomous, environmentally responsible machines powered by renewable energy.
Goffredo Giordano +3 more
doaj +2 more sources
Epidemiology of treatment resistant depression among major depressive disorder patients in Israel [PDF]
Introduction Major depressive disorder (MDD) is one of the most common mental disorders worldwide, estimated to affect 10–15% of the population per year.
Sarah Sharman Moser +5 more
doaj +2 more sources
Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis [PDF]
Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka +12 more
doaj +2 more sources
Retinal drusen in glomerulonephritis with or without immune deposits suggest systemic complement activation in disease pathogenesis [PDF]
Retinal drusen are characteristic of macular degeneration and complement activation, but also occur in C3, lupus and IgA nephropathy. This cross-sectional observational study compared drusen counts in different forms of glomerulonephritis.
P. Harraka +7 more
doaj +2 more sources
Spontaneous bleeding in chronic kidney disease: global coagulation assays may predict bleeding risk [PDF]
Background: Chronic kidney disease (CKD) is associated with increased bleeding and thrombotic risks. Standard blood tests do not sufficiently quantify these risks.
Rowena Brook +4 more
doaj +2 more sources
Determination of Economic Sustainability Factors in Sheep Enterprises in Türkiye [PDF]
Background This study aimed to identify the primary factors influencing the economic sustainability of sheep enterprises in Türkiye. Materials and Methods Data were collected through face‐to‐face surveys conducted with 201 enterprises across Ankara ...
Burak Mat +4 more
doaj +2 more sources
Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue S2, October 2021.
europepmc +2 more sources
Pancreatic hydatid cysts are fairly rare. The disease can be encountered concurrently with systemic involvement or as an isolated pancreatic involvement.
Tugan Tezcaner +4 more
doaj +2 more sources

