Results 251 to 260 of about 360,977 (393)
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source
Evaluating the Safety of Gastrointestinal Contrast Agents in Pediatric Patients: A Retrospective Study. [PDF]
Alshehri A +6 more
europepmc +1 more source
Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao +6 more
wiley +1 more source
Molecular-Scale Analysis of Barium Azide (Ba(N<sub>3</sub>)<sub>2</sub>) Under High Pressure: A Synchrotron X-Ray Diffraction Study on Azide Ion Rotation and Phase Transition. [PDF]
Wu X +8 more
europepmc +1 more source
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel +19 more
wiley +1 more source
High-frequency magnetic properties at K and Ka bands for barium-ferrite/silicone composites
Z.W. Li +3 more
openalex +2 more sources

